ASU MEPN- NUR 545 Pharm Neuro Meds Part 1
Questions And Answers Latest Update
Baclofen (Lioresal)
central acting muscle relaxant
Baclofen (Lioresal) - MOA
acts within the spinal cord to suppress hyperactive reflexes involved in
regulation of muscle movement
Baclofen (Lioresal) - therapeutic outcome:
Decrease the frequency and severity of muscle spasms (MS).
- Spinal cord injury
- Multiple sclerosis
- Cerebral palsy
Baclofen (Lioresal) - contraindications
Hypersensitivity
Concurrent use with MAOIs
, Solution 2024/2025
Pepper
Baclofen (Lioresal) - interactions
Use with alcohol or other CNS depressants can INCREASE sedation
Serotonin syndrome can happen
Baclofen (Lioresal) - Client Education
- Side effects will decrease with time and are minimized by starting at a low
dose
- Change position SLOWLY if experiencing dizziness
- Advise to not drive or perform activities requiring mental alertness if they
are drowsy
- Take with food or milk
- Increase fiber and fluid intake and report constipation to provider
- Do NOT stop taking abruptly; taper doses over 1-2 weeks
Baclofen (Lioresal) - Nurse Interventions
- Low dose and increase gradually
- Give with food
- Monitor for constipation, encourage fluids and increased fiber
- Taper 1-2 weeks
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