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Nur 617 Pharm Exam 1 Questions and Correct Answers the Latest Update $10.49   Add to cart

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Nur 617 Pharm Exam 1 Questions and Correct Answers the Latest Update

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Pharmacogenomics the study of genetically determined variations in the response to drugs Pharmacokinetics The way the body processes drugs. Involves 4 processes of: -absorption -distribution -metabolism -excretion Drug clearance The process of metabolism and excretion/ The disappe...

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  • October 21, 2024
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  • Nur 617
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Nur 617 Pharm Exam 1 Questions and
Correct Answers the Latest Update
Pharmacogenomics

✓ the study of genetically determined variations in the response to drugs



Pharmacokinetics

✓ The way the body processes drugs. Involves 4 processes of:
✓ -absorption
✓ -distribution
✓ -metabolism
✓ -excretion



Drug clearance

✓ The process of metabolism and excretion/
✓ The disappearance of the drug from the patient's serum



Absorption

✓ The process by which drug molecules move from their site of administration, across
one or more cell membranes, in order to gain entry to the blood



Driving force of absorption

✓ Concentration gradient = Concentration on either side of the membrane



Concentration Gradient




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✓ Passive diffusion- from high concentration to low concentration. Does NOT require
energy



Routes of drug administration that do NOT involve the absorption process

✓ -IV
✓ -Intraarterial



Absorption: Fastest to slowest drug formulations

✓ FASTEST
✓ -liquids
✓ -suspensions
✓ -powders

✓ -capsules
✓ -tablets
✓ -enteric coated tablets
✓ -sustained release tablets
✓ SLOWEST



Factors that determine the rate and extent of drug absorption

✓ -solubility (or dissolvability) of the drug
✓ -physical properties of the drug
✓ -area of absorptive surface
✓ -blood supply at absorptive surface
✓ -length of time of contact with absorptive surface



Cell membranes are composed of lipids. --> Fat-soluble molecules cross the

membrane easier than water-soluble. What are fat soluble molecules called?



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