100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
IMM250 PRACTICE EXAM QUESTIONS WITH ALL CORRECT ANSWERS $12.99   Add to cart

Exam (elaborations)

IMM250 PRACTICE EXAM QUESTIONS WITH ALL CORRECT ANSWERS

 4 views  0 purchase
  • Course
  • IMM250
  • Institution
  • IMM250

IMM250 PRACTICE EXAM QUESTIONS WITH ALL CORRECT ANSWERS Mechanisms through which neutrophils can kill microbes - Answer- - Antimicrobial peptides - Lysozyme - ROS (reactive oxygen species) - respiratory burst Reactive oxygen species - Answer- ROS are powerful oxidizing factors that kill pa...

[Show more]

Preview 2 out of 15  pages

  • October 21, 2024
  • 15
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • imm250
  • IMM250
  • IMM250
avatar-seller
Scholarsstudyguide
IMM250 PRACTICE EXAM QUESTIONS
WITH ALL CORRECT ANSWERS

Mechanisms through which neutrophils can kill microbes - Answer- - Antimicrobial
peptides
- Lysozyme
- ROS (reactive oxygen species) - respiratory burst

Reactive oxygen species - Answer- ROS are powerful oxidizing factors that kill
pathogens

- One way that phagocytes kill bacteria is by formation of NADPH oxidase from the
combination of subunits(p67, p47, p40 and p22, gp91) which, with O2 forms ROS.

Chronic Granulomatous Disease (CGD) - Answer- X-linked mutation affecting NADPH
oxidase causing dysfunctioning neutrophils and unable to generate of ROS - so unable
to kill pathogen

3 types of granulocytes - Answer- 1. Neutrophils - pinkish
2. Eosinophils - orange
3. Basophils - purple

Degranulating cells - Answer- for killing of large pathogens

responsible for immediate allergy symptoms to eject parasites from the body, but cause
symptoms of allergy

Mast cells
Basophils
Eosinophils

Cause vasodilation, mucus production, itching and gut mobility

mast cells - Answer- contain granules but not a granulocyte bc not found in blood (is in
tissues)

basophils - Answer- - granulocyte
- least common WBC
- in blood
- produce histamine

, Eosinophils - Answer- - granulocyte
- found in blood but sometimes tissue
- granules contain toxic cationic proteins

FcERI-mediated degranulation of mast cells - Answer- When allergen binds with IgE,
attached on Fc receptor of mast cell. cell is activated and release granules which cause
allergic symptoms

vascular changes in acute inflammation induced by inflammatory cytokines - Answer- -
dilation of vessels
- Increase permeability
- Increase expression of adhesion molecules that trap white blood cells

These changes allow the WBC to rapidly go to the site of infection

chemokines - Answer- A family of small chemotactic cytokines that act to attract other
leukocytes to the site where they are produced

Pro-inflammatory cytokines - Answer- IL-1β, IL-6, IL-12, IL-18, tumor necrosis factor
(TNF), others.
And IL-8, also known as CXCL8 (a chemokine)

3 Pathways of the complement system - Answer- 1. lectin pathway
2. classical pathway
3. alternative pathway

Effector function of complement - Answer- 1. opsonization (C3B) and phagocytosis of
microbes
2. Recruitment of Leukocytes and sites of infection (C3a and C5a)
3. Lysis of bacteria (C5b-9)

C1 inhibitor (C1INH) - Answer- inhibits the activation of C1 complex.

Dissociates C1r/C1s dimers from C1q, and MASP-1/MASP-2 dimers from MBL

This inhibits the classical and lectin pathways of activation

Hereditary Angiodema - Answer- - caused by Genetic deficiency of C1INH.
- Causes swelling

Antiviral function of type I interferons (Type I IFNs) - Answer- Type I IFNs are produced
by virus-infected cells. They bind to the IFN receptor expressed by most cell types and
induce in them an antiviral state.

Type I interferons - Answer- - Antiviral function

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller Scholarsstudyguide. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for $12.99. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

72042 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy study notes for 14 years now

Start selling
$12.99
  • (0)
  Add to cart