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BPS 2110 EXAM QUESTIONS AND ANSWERS
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BPS 2110 EXAM QUESTIONS AND ANSWERSBIOPHARMACEUTICS - ANSWER study of the nature and properties of therapeutics
substances and the relationship between these: dosages and bioactivity.
We used to have only small molecules, then other types of drugs emerged, such as: -
ANSWER - injected biologics
- monoclonal antibodies
- vaccines (huge and heavy molecules)
Therapeutic substances: - ANSWER 1. Prescription drugs
2. Natural Health Products (NHP)
3. Diagnostics
Prescription drugs - ANSWER - Small molecules
- Natural and unnatural peptides
Natural Health Products (NHPS) - ANSWER - Most drugs are found in nature then goes
through a long and expensive process to get into an effective form taken by humans
(500$ to 700$ million on average, paid by pharmaceutical companies).
- Vitamines
- Plant extracts
Most drugs are found in nature, then goes through a long and expensive process to get
into an effective form taken by humans, how much does it cost and who pays? -
ANSWER 500$ to 700$ million on avg., paid by pharmaceutical companies
Diagnostics - ANSWER Vaccines of conjugates, pill that goes through GI tract and takes
,pictures, uploads them automatically so the doc can see the GI tract
What are the different types of Vaccine - ANSWER 1. Attenuated
2. Inactivated
Attenuated vaccine - ANSWER - Comprise of live viruses
- Need to render it less virulent by weakening the virus (denaturing it) so that it does not
cause a disease.
- when somebody's immuniology is compromised (Ex. HIV patients). it doesn't establish
itself So, a passage has to be generated.
Example of attenuated self- vaccine, in which a lot of people died from. - ANSWER polio
Inactive vaccine - ANSWER - Manufactured by growing bacterium or virus in culture and
then inactivating it, killing it by heat or chemicals.
- Provides the body with the opportunity to develop immunity without actually causing a
disease.
PHARMACEUTICAL SCIENCES definition - ANSWER - A group of interdisciplinary areas
of research
- Concerned with:
the design
synthesis
made of action
delivering
and use of drugs.
PHARMACEUTICAL SCIENCES, purposes - ANSWER supplies material and techniques
, that deliver the things that people desire most-> good health.
PHARMACEUTICAL SCIENCES, Aims: - ANSWER- create drugs with min. collateral
damage (difficult to do because humans are complex)
-to treat condition/problem, not cure it
pharmaceutical industry, profit - ANSWER 55 to 85 billions a year
Avermectin - ANSWER for riverblindness donated by Merck in Africa, population was to
poor to pay for it.
Higher standard of living commodities: - ANSWER - Better food knowledge, safe water
and pasteurized milk
Work place infrastructure
Vaccines
Drugs -cures
Diagnostics
Improved medical procedures.
Health Care spending by the government. - ANSWER does NOT CORRELATE to the # of
drugs we have in the market.
The age of people increased since the early 90's. This is due to - ANSWER the need of a
high standard of living.
Pfizer (USA) - ANSWER Rev 70.7 B$ Prof 14.1B$ #employ 137,000
Johnson and Johnson (USA) - ANSWER Rev 63.7 B$ Prof 10.5 B$#employ 119,000
Hoffmann-Laroche (Swiss) - ANSWER Rev. 43.9 Prof 8.1 #employ 78,000
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