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MOD4 (BRS) PCOL Exam Questions With Correct Answers $12.49   Add to cart

Exam (elaborations)

MOD4 (BRS) PCOL Exam Questions With Correct Answers

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  • PCOL
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  • PCOL

MOD4 (BRS) PCOL Exam Questions With Correct Answers A - 1.1. Somatostatin interacts with (a) Gi-protein-coupled receptor (B) Gq-protein-coupled receptor (C) Ligand-activated ion channel (D) Receptor-activated tyrosine kinase (e) Intracellular nuclear receptor C - 1.2. Cortisol is capable of...

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  • October 20, 2024
  • 159
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • PCOL
  • PCOL
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sirjoel
©SIRJOEL EXAM SOLUTIONS
12/3/2024 11:27AM



MOD4 (BRS) PCOL Exam Questions With
Correct Answers


A - 1.1. Somatostatin interacts with

(a) Gi-protein-coupled receptor

(B) Gq-protein-coupled receptor

(C) Ligand-activated ion channel

(D) Receptor-activated tyrosine kinase

(e) Intracellular nuclear receptor

C - 1.2. Cortisol is capable of targeting intranuclear receptors secondary to its ability to

(a) Recruit intracellular kinases

(B) Undergo autophosphorylation

(C) Diffuse through lipid membranes

(D) Interact with G-protein

(e) Interact with AC

C - 1.3. Which of the following parameters is used

, ©SIRJOEL EXAM SOLUTIONS
12/3/2024 11:27AM


to indicate the ability of a drug to produce

the desired therapeutic effect relative to a

toxic effect?

(a) Potency

(B) Intrinsic activity

(C) TI

(D) Efficacy

(e) Bioavailability

B - 1.4. A 64-year-old woman with a history

of multiple abdominal surgeries due to

Crohn's disease presents to the emergency

room with obstipation and feculent emesis.

A diagnosis of small bowel obstruction is

made, and she is taken to the operating

room for lysis of adhesions and resection of stenosed region of small bowel.

Postoperatively, the patient is noted to have

elevated blood pressure, and oral metoprolol

, ©SIRJOEL EXAM SOLUTIONS
12/3/2024 11:27AM


is administered; however, no improvement

of hypertension is observed. This is likely

due to

(a) The first-pass effect

(B) Decreased passage of drug through

intestine

(C) Decreased GI blood flow

(D) Destruction of drug by stomach acid

(e) Increased protein binding of the drug

C - 1.5. An important feature of congestive heart

failure (CHF) regarding drug action is

(a) Impaired blood flow to the intestine

(B) Increased protein binding of various drugs

(C) Increased volume of distribution

(D) Increased drug elimination

(e) Altered drug kinetics

A - 1.6. Which of the following is the term used to

, ©SIRJOEL EXAM SOLUTIONS
12/3/2024 11:27AM


describe the elimination rate via metabolism

catalyzed by alcohol dehydrogenase when

the enzyme is saturated?

(a) Zero-order kinetics

(B) First-order elimination

(C) Clearance

(D) Biotransformation

(e) Redistribution

D - 1.7. A 69-year-old woman is being treated in

the intensive care unit for presumed staphylococcal sepsis. To avoid problems with possible

resistance, she is empirically given IV vancomycin while waiting for the culture results to

come back. Vancomycin is a renally excreted

drug. The patient's routine laboratory workup reveals a creatinine value of 3.2, indicating

acute renal failure. What specific considerations will have to be made with regard to

adjustments of the prescribed medication?

(a) She will have to be switched to an oral (per

nasogastric tube) vancomycin preparation

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