NAPLEX: Pharmacy Foundations Part 2 → ↑ ↓
Exam 100% Correct Answers
The Brain and Spinal Cord - answer What components of the body are NOT included within the
definition of the Peripheral Nervous System (PNS)?
True - answer True or False: Neurotransmitters are released from the pre-sy...
The Brain and Spinal Cord - answer What components of the body are NOT included within the
definition of the Peripheral Nervous System (PNS)?
True - answer True or False: Neurotransmitters are released from the pre-synaptic neuron into
the synaptic cleft, then bind to receptors located on the post-synaptic neurons
Somatic Nervous System
Autonomic Nervous System - answer What are the 2 main systems which compose the
Peripheral Nervous System?
Somatic Nervous System - answer Which component of the Peripheral Nervous System controls
voluntary movement?
Acetylcholine; Nicotinic - answer _________ acts on ___________ receptors in skeletal
muscles to produce voluntary movement.
Autonomic Nervous System - answer Digestion, Cardiac Output, and Blood Pressure are
controlled by what branch of the nervous system?
Acetylcholine - answer Which neurotransmitter is utilized in the transfer of signal from one
neuron to the next in the autonomic nervous system?
Parasympathetic Nervous System
Sympathetic Nervous System - answer What are the 2 divisions of the Autonomic Nervous
System?
Parasympathetic; Sympathetic - answer The _____________ Nervous System is often referred
to as the "rest & digest" system, while the _____________ Nervous System is often referred to
as the "fight or flight" system.
Acetylcholine; Muscarinic - answer _____________ is released onto _____________ receptors
in the Parasympathetic Nervous System.
, SLUDD: Salivation, Lacrimation, Urination, Defecation, Digestion - answer Activation of the
Parasympathetic Nervous System (Muscarinic Receptors) will produce what effects throughout
the body? (5)
Epinephrine/Norepinephrine; adrenergic - answer _____________ is released onto
_____________ receptors in the Sympathetic Nervous System.
Alpha-1, Alpha-2, Beta-1, Beta-2 - answer What receptors may be classified as adrenergic
receptors? (4)
Increased Heart Rate, Blood Pressure, and Bronchodilation
Increased Pupil Dilation
Increased Glucose Production
Reduced Bladder Contraction
Reduced Saliva Production
Reduced Peristalsis - answer Activation of the Sympathetic Nervous System will produce what
effects throughout the body? (8)
False - answer True or False: A non-selective Beta Blocker used to target blood pressure will
have no effect on the lungs
Increased vasoconstriction and blood pressure - answer Activation of alpha-1 receptors will
produce what effects throughout the body?
Reduced cardiac output and heart rate - answer Inhibition of beta-1 receptors will produce what
effects throughout the body?
Bronchoconstriction - answer Inhibition of beta-2 receptors will produce what effects
throughout the body?
Vasodilation, decreased heart rate and blood pressure - answer Activation of alpha-2 receptors
will produce what effects throughout the body?
Sympathetic - answer Activation of alpha-2 receptors reduces the overall output from what
nervous system?
Dopamine
Epinephrine
Norepinephrine
Serotonin
,Tyramine - answer Monoamine Oxidase (MAO) is used to breakdown what catecholamines? (5)
Hypertensive Crisis and Serotonin Syndrome - answer What toxic effects may result from
inhibition of the MAO enzyme?
Phenelzine
Tranylcypromine
Isocarboxazid
Rasagiline
Selegiline
Methylene Blue
Linezolid - answer What agents are known to have MAO inhibitory properties? (7)
True - answer True or False: The specificity of MAO inhibitors for sub-type A or B is dose-
related
Hypertension
Hyperthermia
Tachycardia
Agitation
Coma
Death - answer What are signs and symptoms associated with Hypertensive Crisis? (6)
Tremor
Akathisia
Clonus
Hyperthermia
Sweating - answer What are signs and symptoms associated with Serotonin Syndrome? (5)
at least 14 days - answer When initiating a new mterm-35edication which increases
neurotransmitter levels, how long should the "wash-out" period be following discontinuation of
an MAO inhibitor?
Primary Alcohol - answer Identify the Neutral Functional Group
Ketone - answer Identify the Neutral Functional Group
Aldehyde - answer Identify the Neutral Functional Group
Amide - answer Identify the Neutral Functional Group
, Nitrate - answer Identify the Neutral Functional Group
Nitro - answer Identify the Neutral Functional Group
Benzene - answer Identify the Neutral Functional Group
Urea - answer Identify the Neutral Functional Group
Carbonate - answer Identify the Neutral Functional Group
Carbamate - answer Identify the Neutral Functional Group
Ether - answer Identify the Neutral Functional Group
Thioether - answer Identify the Neutral Functional Group
Carboxyl - answer Identify the Acidic Functional Group
Phenol - answer Identify the Acidic Functional Group
False - answer True or False: an antagonist will behave in a similar manner to an endogenous
substrate
An antagonist blocks an endogenous substrate from binding to its receptor - answer How does
an antagonist work?
Bronchial Smooth Muscle Relaxation - answer Activation of B2-receptors in the lungs would
produce what effect?
Reduced Heart Rate and Contractility - answer Antagonism of B1-receptors in the heart would
produce what effect?
Enzymes catalyze (speed up) reactions - answer What is the purpose of an enzyme?
Competitive Inhibition: A drug binds to the SAME active site as the endogenous substrate
Non-Competitive Inhibition: A drug binds to an ALTERNATIVE site, other than the active site -
answer What is the difference between competitive and non-competitive inhibition of an enzyme
Imide - answer Identify the Acidic Functional Group
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