NAPLEX EXAM WITH QUESTIONS AND ANSWERS ALREADY GRADED A
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Course
NAPLEX E-
Institution
NAPLEX E-
NAPLEX EXAM WITH QUESTIONS AND ANSWERS ALREADY
GRADED A
T or F. Beyond use date must be applied to each compounded product using USP 795 guidelines
for Nonaqueous Liquids and Solid formulation and for Water-containing Formulations. -
ANSWER>>True
Which of the following is considered with...
NAPLEX EXAM WITH QUESTIONS AND ANSWERS ALREADY
GRADED A
T or F. Beyond use date must be applied to each compounded product using USP 795 guidelines
for Nonaqueous Liquids and Solid formulation and for Water-containing Formulations. -
ANSWER>>True
Which of the following is considered with Non-Sterile Preparation? A. USP 795 B. USP 797 -
ANSWER>>A
Labels on Pharmacy-compounded products - Expiration Dates (Beyond Use Dates) -
ANSWER>>* Water containing oral formulations *
> The beyond use date is no later than 14 days when stored at controlled cold temperature
* Water containing topical/dermal/mucosal liquid and semisolid formulations *
> The beyond use date is no later than 30 days
* Nonaqueous formulations*
> The beyond use date is no later than the time remaining until the earliest expiration date of
any API (use no later than 25% of time of this api) or 6 months, whichever is earlier
T or F. For capsules, the label must include mcg or mg/capsule? - ANSWER>>True - Does not
require for tablet
T or F. You can rinse compounding equipment with tap water? - ANSWER>>False - you can
only rinse Purified water for rinsing equipment
What is the best certified sterile compounding environment for injectable product? Which
ISO? - ANSWER>>ISO class 5 (class 100) laminar air flow hood within ISO class 7 (class
10,000) clean room * with positive air pressure * differential relative to adjacent areas.
ISO class 5 (class 100) clean room with positive air pressure differential relative to adjacent
areas or a barrier isolator that provides a ISO class 5 (class 100) environment for compounding
T or F. Liquids in a container curve up, therefore measure at the top of the meniscus. -
ANSWER>>False. Must measure at the bottom of meniscus
,What is the difference between glass and Wedge-wood/Porcelain(ceramic) Mortar and
Pestle? - ANSWER>>wedge-wood or porcelain is used commonly and is best for reducing
particle size of dry powders and crystals
Glass is used for liquids or chemical that are oily or that will stain to the porcelain
T or F. It is safe not to use ointment paper to prepare creams and lotions because these two
formulation have the highest content of water. Water content will cause the paper to moisten, and
possibly tear. - ANSWER>>True. we can use Glassine weighing paper
Which of the following levigating agents are the best to prepare aqueous systems (O/W
dispersions)?
A. Glycerin B. Mineral oil C. Castor oil D. Cottonseed oil E. Tween 80 - ANSWER>>A. Glycerin
> Rest are good levigating agents used to prepare oleaginous systems (W/O)
> Additional agents used as levigating agents to prepare aqueous systems consist of Propylene
glycol, polyethylene glycol 80
Sometimes heat is used to mix things easier, but it lead to over-heating which produce
undesired chemical-reactions. What is the best way to prevent over-heating? - ANSWER>>A
water bath will help prevent over-heating
Fill in the blank
........................ refer to a compound prepared without a specific formula (not from an
official compendium) and made specifically to fill the needs of an individual patient -
ANSWER>>Extemporaneous
Fill in the blank
...................... a single agent that is used to soften and smooth the skin. A moisturizer is
sometimes referred to as ................, but the term is used for single agent, and moisturizers
often have
coloring, scents, and other ingredients added - ANSWER>>Emollients
Fill in the blank
Oil in water , or water in Oil is example of .. - ANSWER>>Emulsions
Fill in the blank
,............ Is used to stabilize the emulsion........ are usually surfactants (wetting agents) that reduce
the
surface tension between the two liquids so that the two different substances can move close to
each other but they will not be mixed together - ANSWER>>Emulsifiers
What is the difference between Continental or dry gum method and English, or wet gum
method? - ANSWER>>Both have same ingredients (oil, purified water and gum (such as
acacia) in the ratio of 4:2:1 but the order of mixing is different.
Dry method: gum is mixed rapidly with oil then water added all at
once Wet method: gum is dissolved in water first, then oil is
slowly added
What you know about HLB (hydrophilic-Lipophilic balance) number? - ANSWER>>#s
range from 0-20 with 10 being the mid-point means it is the break point between water and
oil solubility. #>10 means hydrophilic (water-soluble) and #<10 means lipophilic (lipid-
soluble)
What is Eutectic Mixture? - ANSWER>>A eutectic mixture is two or more components that
melt at a temperature lower than the melting temperature for the individual components.
Which of the following are common preservatives?
A. Benzalkonium chloride (BAK)
B. Benzyl alcohol
C. Chlorhexidine
D. Thimerosal (contain mercury)
E. Sodium benzoate
F. Benzethonium chloride
G. propylparaben - ANSWER>>All of them
Why preservative-free formulations if there is no harm from multi-dose vials? - ANSWER>>no
scientifically conclusive evidence exists of harm from exposure to thimerosal preservative-
containing vaccine, whereas evidence is accumulating of lack of any harm resulting from
exposure to such vaccines. Therefore, the benefits of influenza vaccination outweigh the
theoretical risk, if any, for thimerosal exposure through vaccination" (MMWR 54 [RR08]: 1-40,
2005). Nonetheless, FDA is in discussions with manufacturers of influenza vaccine encouraging
them to further increase the supply of preservative-free formulations.
, Is it safe for pregnant women to receive an influenza vaccine that contains thimerosal? -
ANSWER>>Yes. A study of influenza vaccination examining over 2,000 pregnant women
demonstrated no adverse fetal effects associated with influenza vaccine. Case reports and limited
studies indicate that pregnancy can increase the risk for serious medical complications of
influenza. One study found that out of every 10,000 women in their third trimester of pregnancy
during an average flu season, 25 will be hospitalized for flu related complications.
Which of the following promote a better medication absorption? A. Lotions B. Creams C.
Ointments D. Pastes - ANSWER>>C. Ointments
They are not applied easily to hairy skin
Which of the following has higher potency? A. Elocon (mometasone) ointment B. Elocon
(mometasone) cream - ANSWER>>A. Elocon ointment is high potency and B is low-medium
potency and reason behind this is ointment is 80% oil
Which of the followings is 80% oil and 20% water?
A. Cream
B. Lotion
C. Ointment
D. Paste - ANSWER>>C. Ointment
Cream is 50% oil and 50%
water Lotion is mostly water
Paste are the thickest ointments and are also used as protective barriers Ex. Triple paste
medicated diaper rash ointment
List the 5 classes or types of ointment bases? - ANSWER>>Oleaginous bases such as white
petrolatum Absorption bases (such as lanolin, Aquaphor)
W/O emulsion bases
O/W emulsion bases (hydrophilic ointment,
Dermabase) Water soluble or water miscible bases
(PEG ointment)
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