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Pathophysiology (Exam 1) Cancer Questions with Correct Answers

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What are the difference between benign and malignant tumors? - Answer-- Benign tumors: 1. Well-differentiated cells (Resembles normal cell tissue) 2. Non-invasive; does not destroy surrounding tissues 3. Doesn't break away and spread from tumor cell mass 4. Progressive and slow - Malignant ...

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  • October 18, 2024
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  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • C ANCER
  • C ANCER
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Pathophysiology (Exam 1) Cancer
Questions with Correct Answers
What are the difference between benign and malignant tumors? - Answer-- Benign
tumors:
1. Well-differentiated cells (Resembles normal cell tissue)
2. Non-invasive; does not destroy surrounding tissues
3. Doesn't break away and spread from tumor cell mass
4. Progressive and slow

- Malignant tumors:
1. Range from well-differentiated to poorly differentiated
2. Invasive and are destructive to surrounding tissue
3. Easily breaks free from tumor mass; travels throughout the body in the process of
metastasis frequently
4. Travels through the lymphatic system and blood stream
5. Erratic, and ranges from slow to rapid growth(s)

TNM classification system

- What does each letter in the classification system (T - N - M) stand for? And a
description of each one. - Answer-- T: Tumor size

- N: Lymph node involvement

- M: Metastasis to distant organs
1. Malignant tumors are graded I-III

Briefly describe the grades I-III of metastasis in terms of differentiation. - Answer--
Grade I: Well-differentiated
- Grade II: Moderately-differentiated
- Grade III: Poorly differentiated (Anaplastic cells)

Classes of cancer genes: Tumor suppressor gene

- What is the normal function of a tumor suppressor gene? What happens when it
becomes defective? Name an example of a tumor suppressor gene and briefly describe
its relation to cancer. - Answer-- Normallty function to restrain cell growth

- When defective, it helps in the growth of cancer formation; they lose their ability to
inhibit cell growth

- P53 gene: Half of all cancers have a defective P53 gene
1. Causes cancer cells not to undergo apoptosis; allows them to proliferate and flourish

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