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SPMM Old Age – Questions With Correct Solutions
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SPMM Old Age – Questions With Correct Solutions
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SPMM Old Age – Questions With Correct SolutionsSuicide rate in Huntingtons Right Ans - higher than expected
Location of genetic defect for Huntingtons Right Ans - short arm of
chromosome 4
In which dementia's is recall memory more impaired than recognition
memory? Right Ans - Subcortical dementias e.g. HIV associated dementia
The greatest risk factor for vascular dementia Right Ans - HTN as this is the
greatest risk factor of stroke
What is hyperhomocysteinaemia and how does it relate to dementia? Right
Ans - Elevated plasma total homocysteine which is a modifiable risk factor for
the development of dementia
Most common psychological and behavioural symptom in patient's with
Huntingonts Right Ans - Apathy
What is apathy? Right Ans - a quantifiable reduction in goal-directed
behaviour manifesting as
- reduction in interest
- reduction in spontaneity
- reduction in motivation
- reduction in drive
Type of dementia where tests of attention, visuospatial ability and executive
functioning will show significant deficit? Right Ans - LBD
Most common psychiatric side effects of levo-dopa Right Ans - - nightmares
(most common)
- night terrors
- delirium
- delusional disorder
Neurotransmitters most implicated in AD Right Ans - ACh and
noradrenaline
, Most prevalent PD in older adults Right Ans - obsessive compulsive
In the UK, warnings are currently in place regarding increased mortality and a
possible risk of stroke in patients with dementia who are prescribed what
drug? Right Ans - any first or second generation antipsychotic
Response to antidepressants is particularly poor in which late onset
depression? Right Ans - vascular depression
Normal biological changes in the brain associated with ageing Right Ans - -
decrease in gross brain weight (about 17% by age 80)
- widened sucli, smaller convolutions, gyral atrophy
- enlarged ventricles
- increased transport across BBB
- decreased cerebral blood flow and oxygenation
Risk of AD if you have a first degree relative with it Right Ans - 3x increase
antipsychotics with greatest risk of postural hypothension Right Ans -
clozapine
risperidone
which dementia drug has the most benefit in hallucinations in LBD? Right
Ans - rivastigmine
neuroanatomical changes associated with depression including late onset
Right Ans - ventricular enlagement
Prion diseases Right Ans - - CJD
- fatal familial insomnia
- Gerstmann- Straussler- Scheinker syndrome
- Kuru
Cortical dementias Right Ans - - AD
- frontotemporal
Subcortical dementias Right Ans - - vascular
- progressive supranuclear palsy
- multi system atrophy
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