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SPMM Pharmacodynamics – Questions And Detailed Answers
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SPMM Pharmacodynamics – Questions And Detailed Answers
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SPMM Pharmacodynamics – Questions And DetailedAnswers
How much Zuclo is equivalent to 50mg haloperidol every 4 weeks? Right
Ans - 200mg every 2-4 weeks
What effect of mirtazapine leads to sedation? Right Ans - Blockade of 5HT-
2 receptors
What effect of clozapine leads to weight gain? Right Ans - 5HT2-c
antagonism
Which drugs are comparatively safe to use wih MAOI's? Right Ans - TCA
other than clompiramine
Weak inhibitor of the P450 system Right Ans - Citalopram
Which TCA has a stimulant effect? Right Ans - Desipramine - has relative
selectivity for noradrenaline reuptake
Rare side effect of mirtazapine? Right Ans - Neutropenia
Chronic TCA administration leads to... Right Ans - Downregulation of beta
adrenergic receptors
What happens if you increase amount of agonistic neurotransmitter with a
non-competitive inhibitor in place? Right Ans - The non-competitive
inhibitor will be partially revered
Which medication is effective in premature ejaculation? Right Ans -
Fluoxetine
MOA of cyproheptadine Right Ans - H1 antagonist with nonspecific 5HT
antagonistic properties
Which street drug is a dissociative anaesthetic? Right Ans - Ketamine
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