Different forms of passive transport for drugs - answer-filtration, passive diffusion, convection
Bioavaliability represnts - answer-drug conc in plasma
Drug distribution - answer-albumin is the major binding protein and may act as a drug reservoir
-hydrophobic drugs rapidly move across most...
, Pharmacology mcq's page 1 - 9
Main routes of enteral administration of drugs - answer-oral, rectal, per mucosa
Advantages of oral route of drug admin - answer-easily self administered, toxicity and od overcome with
antidotes
Advantages of rectal route - answer-• used if patient is vomiting or unconscious
Children
Avoid first-pass metabolism
Enteral routes of drug admininistation avoid first pass metabolism of liver - answer-rectal, sublingual
Main routes of paraenteral administation of drug - answer-injection, percutanoues
Paraenteral routes of drug admin - answer-intravenous, intramuscular, intransal
Transdermal, subcutanoues, inhalation
Disadvantages of intravenous drug administration - answer-trained staff required, bacterial
contamination risk @ site of infection, painful and stressful for patient
Correct statements for intravenous drug administration - answer-aqueous solutions can be administered
by iv, highest bioavalilability, treatment of life-threatening conditions
Route of administration for oil solutions - answer-oral, intramuscular, subcutanously
Suspensions can be administered - answer-orally, intramuscularylu and subcutanously
Pharmokinetics - adme - answer-the study of drugs within the body, absorption , distribution,
metabolism, excretion
Pharmokinetic indexes - answer-volume of distro, half life, clearance, bioavaliability
Passive diffusion - answer-does not require energy
Drugs move from higher to lower conc
Diffusion of lipid soluble drugs - answer-depends on charge of drug molecule, penetration through
biological membranes
Drug weak-acid wil be absorbed at - answer-in medium with high ph
In stomach
Drug base acid will be absorbed - answer-in a medium with high ph
- in the intestine
Active drug transport - answer-energy dependent, requires carriers
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