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Psychopharm N358 Exam Questions and Answers Already Passed

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Psychopharm N358 Exam Questions and Answers Already Passed Antidepressant medications classes - Answers MAOIs Tricyclics SNRIs SSRIs Heterocyclics antidepressant medications mechanism of action - Answers increase levels of certain neurotransmitters; predominantly serotonin, norepinephrine an...

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  • October 17, 2024
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  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • Psychopharm N358
  • Psychopharm N358
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Psychopharm N358 Exam Questions and Answers Already Passed

Antidepressant medications classes - Answers MAOIs

Tricyclics

SNRIs

SSRIs

Heterocyclics

antidepressant medications mechanism of action - Answers increase levels of certain neurotransmitters;
predominantly serotonin, norepinephrine and/or dopamine

MAOI food-drug interactions - Answers tyramine containing foods

aged cheeses, red wines, smoked and processed meats, etc.

MAOI drug-drug interactions - Answers all other antidepressants, sympathomimetics, stimulants,
antihypertensives

What is required before switching to MAOIs from another antidepressant? - Answers 2-week wash out
period, or 5 weeks after fluoxetine

What can food and drug interactions with MAOIs cause? - Answers hypertensive crisis

examples of MAOIs - Answers phenelzine (Nardil) and tranylcypromine (Parnate)

contraindications for MAOIs - Answers post-acute myocardial infarction

narrow angle glaucoma

dietary restrictions which which MAOI may not be necessary - Answers selegeline transdermal system
(Emsam) at 6mg/24 hour

modifications recommended at 9mg and 12mg/24 hour

tricyclic antidepressants may also be used for treatment of - Answers chronic pain

What is different about tricyclic antidepressants from SSRIs? - Answers more pronounced side effects
and safety considerations

side effects of tricyclic antidepressants - Answers anticholinergic effects (dry mouth, constipation)

orthostatic hypotension

photosensitivity (eyes and skin)

, risk of potentially fatal overdose in suicide attempts

tricyclic antidepressant examples - Answers amitryptiline

imipramine (Tofranil)

clomipramine (Anafranil) effective in treatment of OCD

what kind of side effect profiles do SSRIs and SNRIs have - Answers benign, safer

when will therapeutic response with SSRIs and SNRIs occur - Answers a few weeks to a few months

characteristics of sertraline - Answers Zoloft - SSRI, among most commonly prescribed

characteristics of fluoxetine - Answers Prozac - SSRI, longer half-life

characteristics of fluvoxamine - Answers Luvox - SSRI, may be used to treat OCD

characteristics of citalopram - Answers Celexa - SSRI, obtain baseline EKG, not dosed higher than
40mg/day because of cardiac effects

characteristics of duloxetine - Answers Cymbalta - SNRI, depression and/or pain

what can occur when duloxetine is discontinued abruptly? - Answers discontinuation syndrome, like the
flu

which antidepressant class is the treatment of choice for long-term management of anxiety disorders -
Answers SSRIs and SNRIs

SSRI and SNRI initial dosing - Answers start low and go slow to avoid initial worsening of symptoms

start at half or less recommended dose

interruption in SSRI and SNRI regimen or abrupt termination may result in - Answers discontinuation
syndrome with flu like symptoms

What puts someone at risk for serotonin syndrome - Answers two or more medications and/or illicit
agents that potentiate serotonergic neurotransmission (St. John's Wort and ecstasy)

symptoms of serotonin syndrome - Answers changes in mental status, restlessness, elevated
temperature, tachycardia, labile blood pressure, diaphoresis, shivering, tremors

treatment for serotonin syndrome - Answers cyproheptadine (Periactin) - histamine 1 receptor
antagonist and supportive measures

examples of heterocyclic antidepressants - Answers bupropion (Wellbutrin)

miratazapine (Remeron)

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