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Psychopharm - Pharmacodynamics Review Questions with Complete Solutions Graded A+

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Psychopharm - Pharmacodynamics Review Questions with Complete Solutions Graded A+ pharmacodynamics - Answers all drug effects, beneficial and undesired, as well as the body's compensatory homeostatic adjustments to the presence of a drug dose - Answers measured quantity of a medicine to be taken ...

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  • October 17, 2024
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  • Psychopharm - Pharmacodynamics
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Psychopharm - Pharmacodynamics Review Questions with Complete Solutions Graded A+

pharmacodynamics - Answers all drug effects, beneficial and undesired, as well as the body's
compensatory homeostatic adjustments to the presence of a drug

dose - Answers measured quantity of a medicine to be taken at 1 time or at stated intervals

concentration - Answers - amt of drug or other substance in a given volume

- amt of drug over unit of volume, i.e. 20mg/ml

threshold dose - Answers a dose of drug just sufficient to produce a pre-selected effect

In pharmacodynamics, what does the "potency" of a drug refer to? - Answers - the relative dose
required to achieve a given effect

- used as a way to compare similar drugs

- ex: Haldol is more potent than Thorazine because it only takes 5mg of Haldol to achieve the same
effects as 100mg of Thorazine

What is the median effective dose of a drug? - Answers the dose of a drug predicted to produce a
characteristic effect in 50% of the subjects to whom the dose is given

What is the median lethal dose of a drug? - Answers dose which produces death in 50% of a (test)
population

therapeutic index of a drug - Answers - the ratio of the median lethal dose to the median effective dose

- measures the safety of a drug

- the higher the therapeutic index, the safer the drug

What is meant by "affinity" when speaking of drug-receptor interactions? - Answers relative strength of
chemical forces that cause the drug to bind to the receptor

What is meant by "efficacy" when speaking of drug-receptor interactions? - Answers - the power of the
drug, through the information encoded in its chemical structure, to activate the receptor when the drug
binds to it

- how good the drug is at making a certain response from the cell

agonist - Answers drugs that produce the same effects, when they bind to a neuroreceptor as does the
natural neurotransmitter

antagonist - Answers - drugs that block the actions of natural neurotransmitters/agonists, partial
agonists, and inverse agonists that are active at the receptor

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