These lecture notes go in depth about the types of bacteria found in the cardiovascular and lymphatic systems. We discuss what they do and how they affect the functions of the human body.
Normal Microflora of Cardiovascular and Lymphatic systems
NONE
Transient Bacteremia: What you hope to find
- hobo: original transient AKA bacteria that travel through cardiovascular and lymphatic
system
- Transient because it comes and goes, if not you’re dead
Septicemia AKA lymphangitis: food poisoning; red line of inflammation that moves from site of
injury down or out
- can lead to SEPTIC SHOCK
- Sx: Fever, low BP (blood vessels begin to collapse which leads to necrosis and
gangrene), red streaks
- Mostly nosocomial
- 50-70% death rate
- Onset: 24 hours
- Diagnose: Blood culture
- Trt: Elevate BP so you can give antibiotics (oral or IV)
Bacterial endocarditis: Bacteria start to inflame the heart, heart lining, or valves.
- Occurs in 45 yrs and up
- Acute cases exist: 33% and kills people within days, ⅔ are subacute ; people experience
fever, malaise, and heart murmur
- Heart valves get damaged by bacterial vegetation
Pericarditis: inflammation of lining around heart
- squeezes heart muscle
- 40% of cases are staphylococcus aureus, untreated mortality is 100%
- With treatment: 20-40% mortality rate
Streptococcus pyogenes: Group A streptococcus
- Doctor Semmelweis
- Has hemolysins for splitting RBCs
- Described by Rebecca Lancefield
- Born 1895 died 1981, she was the president of the American Society of
Microbiology
- Member of National Academy of Sciences and professor at Rockefeller
University
- Classified 50 types of bacteria
- Focus was on bacteria that were pathogenic and causing infectious disease
- Common as repurial (?) fever
- Fever and chills, site is in pelvis though, bloody discharge
- Trt: Antibiotics and might have to use penicillin
- Takes weeks to recover
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