ExamI3:INSGI318/INSG318I(NewI2024/I
2025IUpdate)IPharmacologyI|IGuideIwithI
QsI&IAsI|I100%ICorrect|IGradeIAI
(VerifiedIAnswers)-IGCU
QUESTION
HeparinIClass
Answer:
IAnticoagulant
QUESTION
HeparinIIndication
Answer:
IPreventionIandItreatmentIofIthromboembolicIdisorders
(DVT,IPE,IDIC,Istroke)
QUESTION
HeparinIMOA
Answer:
IInactivatesIthrombin,IwhichIpreventsIconversionIofIfibrinogenItoIfibrin
QUESTION
HeparinISideIEffects
Answer:
,IBleeding,Ihyperkalemia,Iheparin-inducedIthrombocy-
ItopeniaI(HIT),Ihematoma,Ihematuria,ImelenaI(blackItarryIstool)
QUESTION
HeparinINC
Answer:
ICloselyImonitorIaPTT.ITherapeuticIaPTTIisI1.5-
2ItimesIbaseline.IAntidoteIisIprotamineIsulfate!I*ShortItermItherapy*
QUESTION
HeparinIPT
Answer:
IUseIelectricIshaver,IavoidIotherIanticoagulants,IpayIattentionItoIbruises.INOINSAIDsI
orIAspirin!
QUESTION
EnoxaparinI(Lovenox)IClass
Answer:
IAnticoagulant,ILowIMolecularIWeightIHeparin
QUESTION
EnoxaparinIIndication
Answer:
IDVTITreatment/Prophylaxis
QUESTION
,EnoxaparinIMOA
Answer:
IInhibitsIfactorIXaIbyIincreasingIinhibitionIrateIofIclottingIactivatedIbyIantithrombinIII
I
QUESTION
EnoxaparinISideIEffects
Answer:
IBleeding,Ibruising,IinjectionIsiteIhematoma,IInjectionIsiteIecchymosis,Imelena
QUESTION
EnoxaparinINC
Answer:
IMonitorIplateletIcountINOTIaPTT,IonlyIgivenISQI&Ipt'sIcanIgoIhomeIonIitI(adjustIfo
rIrenalIimpairment)
NOINSAIDsIorIAspirinIcanIincreaseItheIriskIofIbleeding.
QUESTION
WarfarinIClass
Answer:
IOralIAnticoagulantICoumarin
QUESTION
WarfarinIIndication
Answer:
ILongItermITherapy.IPreventionIandItreatmentIofIthrom-
IboembolicIdisordersI(exIDVT,IPE),IAFib
, QUESTION
WarfarinIMOA
Answer:
IAntagonizesIvitaminIKI&IinhibitsIprothrombin,IpreventingIforma-
ItionIofIseveralIclottingIfactors.
Tip:IWARfarinIisIgoingItoIWARIwithIvitaminIK
QUESTION
WarfarinISideIEffects
Answer:
IGIIupset,Ihepatitis,Ialopecia,Ifever,Iweakness,Ipriapism,IpurpleItoeIsyndrome
Warning:ILife-threatingIbleedingI(Hemorrhage)
QUESTION
WarfarinINC
Answer:
ICloselyImonitorIPT/INRIlevels.ITherapeuticIINRIisI2-3I(takesI5-
7IdaysItoIgetItoIaItherapeuticIlevel).IAntidoteIVitaminIK!
QUESTION
WarfarinIPT
Answer:
IMaintainIaIconsistentIdietaryIintakeIofIvitaminIK.IAvoidINSAIDs
QUESTION