1. Which cannabinoid is most commonly associated with pain relief?
o A. Tetrahydrocannabinol (THC)
o B. Cannabidiol (CBD)
o C. Cannabinol (CBN)
o D. Delta-8-tetrahydrocannabinol (Delta-8 THC)
Answer: A. Tetrahydrocannabinol (THC)
Rationale: THC is the primary psychoactive compound in cannabis...
NCLEX-Style Questions on Cannabinoids for Pain Management
1. Which cannabinoid is most commonly associated with pain relief?
o A. Tetrahydrocannabinol (THC)
o B. Cannabidiol (CBD)
o C. Cannabinol (CBN)
o D. Delta-8-tetrahydrocannabinol (Delta-8 THC)
Answer: A. Tetrahydrocannabinol (THC)
Rationale: THC is the primary psychoactive compound in cannabis and is known for its
analgesic properties.
2. What is a common side effect of cannabinoids used in pain management?
o A. Nausea
o B. Increased heart rate
o C. Respiratory depression
o D. Hypotension
Answer: B. Increased heart rate
Rationale: Cannabinoids can cause tachycardia as a side effect, which is important for
nurses to monitor in patients.
3. When teaching a patient about using cannabis for chronic pain management, which
statement is most appropriate?
o A. "Cannabis will cure your pain completely."
o B. "You can use cannabis in any amount without side effects."
o C. "It may take time to find the right dose that works for you."
o D. "Cannabis is completely safe for everyone."
Answer: C. "It may take time to find the right dose that works for you."
Rationale: Individual responses to cannabinoids can vary widely, and titration to an
effective dose is often necessary.
4. Which route of administration for cannabinoids is considered the fastest for pain
relief?
o A. Oral
o B. Inhalation
o C. Sublingual
, o D. Topical
Answer: B. Inhalation
Rationale: Inhalation provides rapid onset of effects, making it suitable for acute pain
management.
5. What is the primary mechanism of action of THC in pain management?
o A. Inhibition of cyclooxygenase
o B. Activation of cannabinoid receptors
o C. Enhancement of opioid receptors
o D. Inhibition of serotonin reuptake
Answer: B. Activation of cannabinoid receptors
Rationale: THC primarily works by binding to cannabinoid receptors in the central
nervous system, affecting pain perception.
6. A nurse is assessing a patient who has been prescribed CBD for chronic pain. Which
potential effect should the nurse monitor for?
o A. Sedation
o B. Hypertension
o C. Constipation
o D. Hallucinations
Answer: A. Sedation
Rationale: CBD can cause drowsiness in some patients; monitoring for sedation is
important.
7. Which condition has been shown to respond well to cannabinoid treatment?
o A. Migraine headaches
o B. Osteoarthritis
o C. Cancer-related pain
o D. All of the above
Answer: D. All of the above
Rationale: Cannabinoids have shown efficacy in managing various pain conditions,
including migraines, osteoarthritis, and cancer pain.
, 8. A patient with a history of substance abuse is prescribed a cannabinoid for pain
management. What is the nurse's priority action?
o A. Administer the medication as prescribed.
o B. Educate the patient about the risks of dependence.
o C. Consult with the healthcare provider about alternative pain management
options.
o D. Monitor the patient closely for signs of intoxication.
Answer: C. Consult with the healthcare provider about alternative pain
management options.
Rationale: Given the patient's history of substance abuse, exploring alternative pain
management strategies may be safer.
9. Which patient teaching point should be included regarding the use of medical
cannabis?
o A. "It is legal in all states."
o B. "You can drive after using it."
o C. "Always keep it out of reach of children."
o D. "There are no drug interactions."
Answer: C. "Always keep it out of reach of children."
Rationale: Safety precautions are essential, especially to prevent accidental ingestion by
children.
10. What is a critical nursing consideration when administering cannabinoids to older
adults?
o A. Older adults do not metabolize cannabinoids differently than younger adults.
o B. There is an increased risk of falls and sedation.
o C. Cannabinoids are contraindicated in this population.
o D. Older adults typically require higher doses than younger patients.
Answer: B. There is an increased risk of falls and sedation.
Rationale: Older adults may have increased sensitivity to cannabinoids, leading to a
higher risk of sedation and falls.
11. A patient reports using cannabis oil for pain relief. The nurse should assess the
patient for which of the following?
o A. Allergic reactions
o B. Euphoria
o C. Withdrawal symptoms
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