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NU 608 Final Exam Study Guide with complete solutions

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NU 608 Final Exam Study Guide with complete solutions Primary function of the pulmonary system: - Answer-Exchange of gases between the environmental air and the blood Three steps involved in exchange of gases in the pulmonary system: - Answer-1. Ventilation- air movement 2. Diffusion- movemen...

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NU 608 Final Exam Study Guide with
complete solutions

Primary function of the pulmonary system: - Answer✔✔-Exchange of gases between the

environmental air and the blood


Three steps involved in exchange of gases in the pulmonary system: - Answer✔✔-1. Ventilation-

air movement


2. Diffusion- movement of gas between air spaces in the lungs and bloodstream


3. Perfusion- movement of blood in an out of the capillary beds of the lungs to the body organs

and tissues


Upper conducting airways (2): - Answer✔✔-Nasopharynx and oropharynx which filter and

moisturize air that is inhaled


Lower conducting airways (3) - Answer✔✔-Larynx (connects the two airways), trachea, and

bronchi.


Primary gas exchange units of the lungs: - Answer✔✔-Alveoli- where oxygen enters the blood

and co2 is removed. Lung contains 25 million alveoli at birth and 300 million by adulthood.


Pulmonary circulation facilitates (4): - Answer✔✔-1. gas exchange


2. delivery of nutrients to the lungs

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3. acts as a reservoir for the left ventricle


4. serves as a filtering system removing clots, air, debris


Gas exchange occurs over what membrane: - Answer✔✔-Respiratory membrane or alveolo-

capillary membrane.


Factors determining how rapidly gas will pass through the respiratory membrane (4): -

Answer✔✔-1. thickness of the membrane (thicker in edema, fibrosis)


2. surface area of membrane (decreased in emphysema, atelectesis)


3. diffusion coefficient of the gas (solubility of gas in the membrane)


4. pressure difference between the two sides of the membrane (gas moves from an area of

higher to lower concentration)


Ventilation: - Answer✔✔-Mechanical movement of gas in and out of lung. Controlled by the

respiratory center in the lower brain stem through the transmission of impulses to the

respiratory muscles based on information from peripheral chemoreceptors and lung receptors.


Lung receptors (3 types): - Answer✔✔-Send impulses from the lungs to the dorsal respiratory

group located in the brain stem.


1. irritant receptors (sensitive to noxious stimuli (pollen, smoke, perfume) that initiate cough

reflex and increase respiratory rate to protect and rid the body of irritant. Cause

bronchoconstriction to attempt to prevent the irritant from going to the lower respiratory tract.




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2. stretch receptors (located in the smooth muscle of airways, control volume of lungs, Hering-

Breuer reflex is a protective mechanism to prevent over inflation)


3. J-receptors (sensitive to increases in capillary pressure, stimulating lungs to initiate rapid,

shallow respiration)


Chemoreceptors- central and peripheral: - Answer✔✔-1. central- located in the medulla.

Respond to changes in the hydrogen ion concentration of the CSF which reflects Co2 levels,

causing changes in breathing.


2. peripheral- located in the aortic bodies and carotids. Sensitive to changes in po2.


Alveolar surface tension: - Answer✔✔-Surfactant is responsible for lowering surface tension.

Surface tension refers to the tendency of water molecules to pull toward each other and

collapse. Surfactant works by forming a layer at the interface between the fluid lining the alveoli

and the air in the alveoli. Primary function of surfactant is to stabilize the alveoli at low lung

volumes and prevent collapse.


Ventilation- Compliance: - Answer✔✔-Measure of lung and chest wall distensibility, so the ease

in which these structures can be stretched and is determined by alveolar surface tension and

elastic recoil of the lung and chest wall.


Increased compliance = lungs are abnormally easy to inflate and lost elastic recoil (emphysema)


Decreased compliance = lungs are stiff and difficult to inflate (fibrosis, ARDS, pneumonia)


Hypoxia: - Answer✔✔-Reduced oxygenation of cells in tissues



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