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NU 607 Module 2 Study Guide with Complete Solutions

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NU 607 Module 2 Study Guide with Complete Solutions Pharmacodynamics - Answer-the study of the biochemical and physiologic effects of drugs and the molecular mechanisms by which those effects are produced; study of what drugs do to the body and how they do it Mechanisms of action - Answer-ways...

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  • October 16, 2024
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EMILLECT 2024/2025 ACADEMIC YEAR ©2024 EMILLECT. ALL RIGHTS RESERVED FIRST PUBLISH OCTOBER, 2024




NU 607 Module 2 Study Guide with
Complete Solutions

Pharmacodynamics - Answer✔✔-the study of the biochemical and physiologic effects of drugs

and the molecular mechanisms by which those effects are produced; study of what drugs do to

the body and how they do it


Mechanisms of action - Answer✔✔-ways by which drugs can produce therapeutic effects; once

the drug is at the site of action, it can increase or decrease the rate at which cells or tissues

function


Dose-response relationship - Answer✔✔-the relationship between the size of an administered

dose and the intensity of the response produced


Efficacy - Answer✔✔-the largest effect that a drug can produce


True/False: A drug with a very high maximal efficacy does not mean it is always more desirable

than one with a lower efficacy - Answer✔✔-True


Potency - Answer✔✔-the amount of drug we must give to elicit an effect


True/False: A drug that is more potent will produce a therapeutic effect at a lower dose

compared to a drug with the higher dose - Answer✔✔-True




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, EMILLECT 2024/2025 ACADEMIC YEAR ©2024 EMILLECT. ALL RIGHTS RESERVED FIRST PUBLISH OCTOBER, 2024


Drugs act through receptors by binding to them. By binding to the receptor, the drug can do

what 2 things? - Answer✔✔-1. initiate (produce) a response


2. block (prevent) a response


Affinity - Answer✔✔-the degree to which a drug molecule binds to a receptor and elicits a

response; the strength of the attraction between a drug & its receptor


Drug binding sites are primarily on __________, ___________, and _______________ -

Answer✔✔-transmembrane proteins, glycoproteins, enzymes


4 primary receptor families - Answer✔✔-Cell membrane-embedded enzymes


Ligand-gated ion channels


G protein-coupled receptor systems


Transcription factors (nuclear receptors)


Cell membrane-embedded enzymes - Answer✔✔-Receptors that span the cell membrane;

domain is located on the cell surface with the enzyme's catalytic site inside; response occurs in

seconds. i.e. insulin


Ligand-gated ion channel - Answer✔✔-receptors that span the cell membrane, function to

regulate flow of ions into and out of cells. each channel is specific for a particular ion. domain is

located on the cell surface. responses to activation are extremely fast, usually occurring in

milliseconds




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