Rosalind Franklin and Maurice Wilkins - ️️DNA is a multiple-stranded fiber of 20 A
thickness. Groups spaced 3.4 A along the fiber and a repeating unit every 34 A.
Purines - ️️Two fused heterocyclic rings
A, G
Pyrimidines - ️️One single heterocyclic ring
T, U, C
Nucleotide Sugars -...
Genetics PCB 3063 Exam 3
Rosalind Franklin and Maurice Wilkins - ✔️✔️DNA is a multiple-stranded fiber of 20 A
thickness. Groups spaced 3.4 A along the fiber and a repeating unit every 34 A.
Purines - ✔️✔️Two fused heterocyclic rings
A, G
Pyrimidines - ✔️✔️One single heterocyclic ring
T, U, C
Nucleotide Sugars - ✔️✔️Ribose
Deoxyribose (Base is always attached to C-1' of the sugar.
Phosphates - ✔️✔️Can be attached to the C-5' of the sugar.
A-DNA - ✔️✔️11bp/turn; 23 A diameter
Prevalent under high salt concentrations/low water conditions.
Doubtful to occur under biological conditions.
C-DNA - ✔️✔️9.3bp/turn; 19A diamether
Prevalent under great dehydration conditions
Doubtful to occur under biological conditions.
Z-DNA - ✔️✔️Prevalent in vitro in C-G containing DNA.
Left-handed.
12bp/turn; 18 A diameter
Zig-Zag conformation
May be involved in regulating gene expression in vivo.
RNA Structure - ✔️✔️Ribose
A=U
C=G
Usually single stranded, but can form short ds regions.
RNA Double Helix - ✔️✔️Right handed
A form. 11-12 base pairs per turn.
What is the structural difference between the sugar found in RNA and the sugar found
in DNA? - ✔️✔️The presence of a 2' hydroxyl.
What order of atoms correctly describes the backbone of a DNA strand? - ✔️✔️3'C-O-
P-O-5'C
What aspect of the sugar is unique to RNA? - ✔️✔️It contains an OH group on the
number 2' carbon of the pentose sugar.
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