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Nurs 316 Final Exam questions with correct answers.
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Nurs 316 Final Exam questions with correct answers.
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Nurs 316 Final Exam questions with correct answersPotency Correct Answer-the AMOUNT of drug necessary to produce
the desired effect
Efficacy Correct Answer-the ABILITY of the drug to achieve the
desired effect
What is the FDA? When was it empowered? What was it empowered to
enforce? What are the primary responsibilities of the FDA? Correct
Answer-
What are the four (4) processes involved with the movement of drugs
inside the body? Correct Answer-1. Absorption
2. Distribution
3. Metabolism
4. Excretion
How does the route of administration effect the action of a drug in a
patient? Correct Answer-• Drugs that are administered IM or SQ are
absorbed by the small capillaries fairly rapidly
• Drugs that are administered oral take the longest to be absorbed
• Drugs that are administered IV do not need to be absorbed and are
instantly absorbed
,What does the amount of protein binding have to do with a drugs rate of
distribution? Rate of excretion? Correct Answer-• The % of drug bound
to albumin is determined by strength of attraction between them
• Only un-bound (free) drugs can leave the vascular space and reach
target tissues
• The portion of the drug that is protein bound is inactive
• Only free drugs are active drugs that can exert a pharmacological effect
Which type of drug is excreted by the kidney with greater ease? (fat-
soluble or water-soluble) Correct Answer-• Lipid soluble drugs are
converted by the liver to water soluble forms for renal excretion
• In kidneys, drugs in a lipid-soluble state will be reabsorbed back into
the blood
• ***So, water soluble drugs are excreted by the kidney with greater
ease
What is the primary organ responsible for drug metabolism? Correct
Answer-Liver
Which drug will need to be dosed more frequently, one with a long half-
life or one with a short half-life? Why? Correct Answer-One with a short
life span, because those are the light protein bound
What is the primary organ responsible for drug excretion? Correct
Answer-Kidney
, Glomerular filtration: Correct Answer-is the process that your kidneys
use to filter excess fluid and waste products out of the blood into the
urine collecting tubules of the kidney, so they may be eliminated from
your body.
Tubular reabsorption: Correct Answer-the process by which solutes and
water are removed from the tubular fluid and transported into the blood.
Tubular secretion: Correct Answer-the transfer of materials from
peritubular capillaries to renal tubular lumen
How will drug excretion by affected in a patient with renal dysfunction?
What risk does this place on the patient? Correct Answer-If patient has
renal failure, then drug stays in the body longer and the patient is at risk
for drug toxicity
If someone has head trauma, will drugs pass the BBB easily or no?
Correct Answer-yes they will pass the BBB more easily
first-pass effect: Correct Answer-Where the portal circulation serves to
protect the body from systemic effects of ingested toxins by delivering
these substances to the liver for detoxification (concentration of drug is
greatly reduced before it reaches the systemic circulation)
peak level: Correct Answer-Highest plasma drug level that indicate the
rate of absorption
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