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Exam (elaborations)

Anki/Pathoma Questions and Answers

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  • Pathoma
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Anki/Pathoma Questions and Answers

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  • October 14, 2024
  • 19
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • Pathoma
  • Pathoma
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Anki/Pathoma Questions and Answers

Which form of Crigler-Najjar syndrome is more severe ? Correct Ans-Type I




What are the treatments (2) for Crigler-Najjar syndrome type I ? Correct Ans-
plasmapheresis and phototherapy



Crigler-Najjar syndrome type II is _______ severe and responds to ________which increases
liver enzyme synthesis Correct Ans-less; phenobarbital ,




________ syndrome is due to a deficiency of bilirubin canalicular transport protein Correct
Ans-Dubin-Johnson




Does Dubin-Johnson syndrome result in unconjugated or conjugated hyperbilirubinemia ?
Correct Ans-Conjugated




Dubin-Johnson syndrome presents with a _______, but is otherwise not clinically significant
Correct Ans-grossly black liver




_______ is similar to Dubin-Johnson syndrome , but milder and Correct Ans-Rotor
syndrome; WITHOUT black liver




Does Rotor syndrome result in unconjugated or conjugated hyperbilirubinemia ? Correct
Ans-Conjugated

, Anki/Pathoma Questions and Answers

What type of jaundice is associated with gallstones , parasites , and liver fluke ? Correct
Ans-Obstructive jaundice




What type of jaundice is associated with cholangiocarcinoma and pancreatic carcinoma ?
Correct Ans-Obstructive jaundice




Does biliary tract obstruction (obstructive jaundice) result in unconjugated or conjugated
hyperbilirubinemia ? Correct Ans-Conjugated




Obstructive jaundice is associated with dark urine due to Correct Ans-increased urine
conjugated bilirubin




Obstructive jaundice is associated with_____ urine urobilinogen Correct Ans-decreased




Obstructive jaundice is associated with _____ stools Correct Ans-pale




Obstructive jaundice is associated with increased serum bile acids , which may cause _______
Correct Ans-pruritus




Obstructive jaundice is associated with_______ , which may cause xanthomas skin finding
Correct Ans-hypercholesterolemia

, Anki/Pathoma Questions and Answers
Obstructive jaundice is associated with ______, GI symptom , with malabsorption of fat-
soluble vitamins Correct Ans-steatorrhea




Does viral hepatitis result in unconjugated or conjugated hyperbilirubinemia ? Correct Ans-
Both




Viral hepatitis is associated with _____ urine due to increased urine conjugated bilirubin
Correct Ans-dark




Viral hepatitis is associated with ______ urine urobilinogen Correct Ans-normal or
decreased




In addition to hepatitis virus , viral hepatitis may also be caused by (2 viruses) Correct Ans-
EBV and CMV




Viral hepatitis is characterized by elevated liver enzymes with Correct Ans-ALT AST




Acute hepatitis is associated with inflammation that involves the lobules of the liver and
portal tracts ; characterized by Correct Ans-apoptosis of hepatocytes




Jaundice is a yellow discoloration of the skin and/or sclera Correct Ans-




What is the earliest sign of jaundice? Correct Ans-Scleral icterus

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