NR546 Advanced Pharmacology:
Psychopharmacology for
Psychiatric-Mental Health Nurse
Practitioner
Week 1
When prescribing medications, what must the psychiatric mental health
nurse practitioner (PMHNP) consider?
The patients:
symptoms
age
physical health
previous response to treatment
lifestyle
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Brainpower
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What is the priority data used to determine a treatment plan for mental
health disorders?
Patient symptoms
Changes or losses in grey matter can be associated with psychiatric
diagnoses such as?
,Alzheimer's disease, schizophrenia, and major depressive disorder.
Many psychotropic medications can cause weight gain. True of False.
True, caution is taken when prescribing to obese patients.
Which lifespan group respond differently to drugs than adults, have
heightened drug sensitivity, show greater individual variation, and have
increased risk for adverse drug reactions? Dosage selection can be
challenging because their brains and bodies are still developing.
Pediatric patients
Which lifespan group have several psychotropic drugs that are not safe to
use, certain drugs resulting in birth defects and certain drugs presenting
in breastmilk, affecting the breastfed child, or affecting milk production?
Pregnancy/breastfeeding patients
The physiologic changes associated with aging impact the drug processes
of absorption, distribution, metabolism, and excretion of medications, so
lower than normal dosages may be needed. The most recent Beers Criteria
should be reviewed to avoid prescribing potentially inappropriate
medications to this lifespan group.
Older adult patients
Brain tissue composed of gray matter includes?
The cerebellum, cerebrum, brain stem, and butterfly-shaped portion of the
central spinal cord.
The gray matter of the brain focuses on?
Psychiatry and neurology and is associated with learning.
Brain tissue composed of white matter includes?
Nerve fibers that connect neurons from different regions into functional
circuits.
Why is white matter considered the transit system?
Necessary for electrical impulse transmission. If there are breaks in the
system, it can affect neural communication, affecting behavior. Damage to
the myelin can impair transmission which can impact not only sensory and
motor function, but also cognition.
White brain matter is associated with which disease processes?
Autism and vascular dementia.
Frontal Lobe
, Associated with movement, intelligence, abstract thinking. the ability to
organize, personality, behavior, and emotional control. Traumatic brain
injuries can result in personality changes, difficulty controlling emotions,
and other cognitive functions.
Parietal Lobe
Middle part of the brain
Responsible for proprioception.
Helps a person to identify spatial relationships, interpret pain and touch in
the body, and identify and give meaning to objects.
Damage to the anterior portion of the parietal lobe may cause
asterogenesis, the loss of ability to recognize objects via the sense of
touch.
May be experienced post cerebral vascular accidents.
Temporal Lobe
Located on the sides of the brain
Involved in short-term memory, speech, auditory signals, and smell
recognition.
Identifies "what" things are - object identification.
Contains the limbic system, amygdala, and hippocampus.
A dominant temporal lobe lesion can present as Wernicke's aphasia.
Temporal Lobe Disorders
Temporal lobe disorders include dementia, affective disorders, and
attention deficit hyperactivity disorders (ADHD).
Occipital Lobe
Back part of the brain and controls visual processing. Damage to this lobe
results in the inability to form visual memories.
Bilateral lobe damage results in the inability to recognize items by sight
even though vision is normal.
Occipital lobe seizures can cause hallucinations, such as lines of color.
Dorsal Striatum
Complex motor actions and linkage of cognition to motor actions.
Main input area for the basal ganglia and is activated when anticipating or
engaging in pleasure.
Corpus Callosum
Controls the communication between the two brain hemispheres.
Involved in attention, impulse control, and emotion regulation.
Integrates impulses from both sides of the brain.
Persons with an underdeveloped or missing corpus collosum may have
intellectual impairment.