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CHT exam 2024- Questions and Answers 100% Solved

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CHT exam 2024- Questions and Answers 100% Solved

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  • October 14, 2024
  • 91
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • CHT
  • CHT
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CHT exam 2024- Questions and Answers 100% Solved

The primary role of the proteasome in antigen presentation is to



a. Prevent premature folding of MHC class I molecules

b. Process cytoplasmic proteins

c. Degrade recycled MHC molecules

d. Bind HLA-DM in the endosome

e. Chaperone peptides to the cell surface Correct Ans-b. Process cytoplasmic proteins




Peptides that bind to MHC class I molecules differ from peptides that bind to MHC class II
molecules in all except which of the following ways?




a. They are shorter

b. They were processed by different proteases

c. They anchor in the middle instead of the end of the MHC molecule

d. They interact with different subsets of T cells Correct Ans-c. They anchor in the middle
instead of the end of the MHC molecule




HLA-DM is primarily involved in the



a. Activation of cytotoxic T cells

b. Loading antigen onto HLA-DR molecules

, CHT exam 2024- Questions and Answers 100% Solved
c. Preventing HLA-A molecules from folding prior to antigen binding

d. Rejection of islet grafts

e. Induction of diabetes mellitus Correct Ans-b. Loading antigen onto HLA-DR molecules




Which of the following is not a secondary lymphoid organ?




a. Spleen

b. Thymus

c. Lymph nodes

d. Liver

e. Tonsils Correct Ans-b. Thymus




Which of the following is not a component of the reticuloendothelial cell system?



a. Microglial cells

b. Kupffer cells

c. Langerhans cells

d. Neutrophils

e. Monocytes Correct Ans-d. Neutrophils




Opsonization is a term to describe what?

, CHT exam 2024- Questions and Answers 100% Solved

a. Lysis of bacteria

b. Coating of bacteria

c. Ingestion of bacteria

d. Killing of bacteria

e. Phagocytosis Correct Ans-b. Coating of bacteria




Which of the following does not describe a role of antibodies in host defense?



a. They serve as a bridge between bacteria and phagocytes

b. They lyse bacteria

c. They enhance complement binding to the bacterial cell wall

d. They prevent viruses from infecting cells

e. They bind pathogens in mucus secretions Correct Ans-b. They lyse bacteria




MHC Class I and II molecules differ in all of the following except



a. Types of T cells they stimulate

b. Types of cells they are expressed on

c. Which chromosome they are located on

d. Types of antigens they present

, CHT exam 2024- Questions and Answers 100% Solved
e. Whether or not they have foreign peptides in the antigen-binding groove Correct Ans-c.
Which chromosome they are located on




The antigen-binding site of an antibody is comprised of which of the following?



a. The variable region of the light and heavy chains

b. The variable region of the light chain only

c. The entire light chain

d. The entire heavy chain

e. The Fc portion of the immunoglobulin molecule Correct Ans-a. The variable region of
the light and heavy chains



The immunoglobulin that binds the most complement is




a. IgA

b. IgD

c. IgM

d. IgG2

e. IgE Correct Ans-c. IgM




The immunoglobulin responsible for activating mast cells in an allergic response is

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