Preformed HLA antibodies in the transplant candidate that are directed against mismatched
HLA in a potential donor can cause?
A. Hyperacute rejection
B. T cell mediated rejection
C. A delay in engraftment of the kidney
D. Chronic rejection
E. All of the above Correct Ans-A. Hyperacute rejection
Where in the cell does transcription (transferring information from DNA to mRNA) take place?
A. Nucleus
B. Cytoplasm
C. Endoplasmic reticulum
D. Golgi apparatus
E. Lysosome Correct Ans-A. Nucleus
Which of the following is NOT true about the genetic code?
A. Each codon is 3 letters long
B. There are codons that "tell" the ribosome to terminate synthesis
C. Each amino acid is specified by only a single codon
D. A codon in the mRNA might be GUA, corresponding to GTA in the DNA
, ASHI CHT EXAM PRACTICE QUESTIONS & ANSWERS
E. Ribosomes read the code during protein synthesis Correct Ans-C. Each amino acid is
specified by only a single codon
How many hydrogen bonds link the nucleotide bases G and T in double stranded DNA?
A. 4
B. 3
C. 2
D. 1
E. 0 Correct Ans-E. 0
Which amino acid can form disulfide bonds?
A. Leucine
B. Cysteine
C. Phenylalanine
D. Valine
E. Glutamic acid Correct Ans-B. Cysteine
What is the term used to characterize an amino acid that prefers to be on the interior of a
protein, hidden away from water?
A. Polar
B. Hydrophobic
C. Positively charged
, ASHI CHT EXAM PRACTICE QUESTIONS & ANSWERS
D. Negatively charged
E. Hydrophilic Correct Ans-B. Hydrophobic
What is the name of the RNA that carries the amino acids to the ribosome during protein
synthesis?
A. mRNA
B. microRNA
C. rRNA
D. tRNA
E. cRNA Correct Ans-D. tRNA
How many pairs of chromosomes are found in a human cell?
A. 10 pairs
B. 16 pairs
C. 23 pairs
D. 28 pairs
E. 32 pairs Correct Ans-C. 23 pairs
If one strand of DNA has the following sequence: 5'AGTAAGC3', what is the sequence of its
complementary strand?
A. 5'AGTAAGC3'
B. 3'AGTAAGC5'
, ASHI CHT EXAM PRACTICE QUESTIONS & ANSWERS
C. 5'TCATTCG3'
D. 3'TCATTCG5'
E. Can't tell, could be anything Correct Ans-D. 3'TCATTCG5'
Which part(s) of a gene specify the protein sequence?
A. Exons
B. Introns
C. Exons and introns
D. Promoter region
E. Exons, introns, and promoter region Correct Ans-A. Exons
The combination of a sugar (ribose), phosphate, and a base is part of the structure of what
macromolecule?
A. Protein
B. DNA
C. RNA Correct Ans-C. RNA
Who performed the first live donor kidney transplant in humans?
A. James D. Hardy
B. Thomas Starzl
C. Joseph E. Murray Correct Ans-C. Joseph E. Murray
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