, Test ABank
to Aaccompany
Psychopharmacology, AThird AEdition
Meyer A• AQuenzer
Chapter A1: APrinciples Aof APharmacology
Multiple AChoice
1. A refer(s) Ato Aspecific Amolecular Achanges Athat Aoccur Awhen Aa Adrug
Abinds Ato Aa Aparticular Atarget Asite Aor Areceptor, Awhile are Athe Aresulting
Awidespread AalterationsAin Afunction.
a. Drug Aaction; Atherapeutic Aeffects
b. Side Aeffects; Adrug Aeffects
c. Therapeutic Aeffects; Aside Aeffects
d. Drug Aaction; Adrug Aeffects
Answer: Ad
Textbook AReference: APharmacology: AThe AScience Aof ADrug AAction
2. After Adrug Aadministration Ahas Aoccurred, Athe Aamount Aof Adrug Ain Athe Ablood
Athat Ais Afree AtoAbind Aat Aspecific Atarget Asites Ais Areferred Ato Aas
a. the Atherapeutic Adose.
b. first-pass Aeffects.
c. bioavailability.
d. ED50.
Answer: Ac
Textbook AReference: APharmacokinetic AFactors ADetermining ADrug AAction
3. The Aspecific Amolecular Achanges Athat Aoccur Awhen Aa Adrug Abinds Ato Aa
Aparticular Atarget AsiteAor Areceptor Aare Areferred Ato Aas
a. drug Aeffects.
b. drug Aaction.
c. side Aeffects.
d. placebo Aeffects.
Answer: Ab
Textbook AReference: APharmacology: AThe AScience Aof ADrug AAction
4. Which Aof Athe Afollowing Ais Anot Aa Apossible Aexplanation Afor Aplacebo Aeffects?
a. Pavlovian Aconditioning
b. Genetic Avariation
c. Drug Acompetition
d. Expectation Aof Aoutcome
Answer: Ac
Textbook AReference: APharmacology: AThe AScience Aof ADrug AAction
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,5. The administration Aof Aoxytocin Ahas Abeen Aproposed Aas Aa Atreatment Afor
Aautism.
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: Ac
Textbook AReference: APharmacokinetic AFactors ADetermining ADrug AAction
6. Which Afactor Adoes Anot Aaffect Athe Apharmacokinetics Aof Aa Adrug?
a. Route Aof Aadministration
b. Lipid Asolubility
c. Depot Abinding
d. Drug Aaction
Answer: Ad
Textbook AReference: APharmacokinetic AFactors ADetermining ADrug AAction
7. First-pass Ametabolism Aoccurs Awhen Adrugs Aare Ataken
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: Aa
Textbook AReference: APharmacokinetic AFactors ADetermining ADrug AAction
8. The Aarea Apostrema Ais Aone Aarea Ain Athe Abrain Awhere Athe is Anot Acomplete.
a. cerebrospinal Afluid
b. blood–brain Abarrier
c. choroid Aplexus
d. phospholipid Amembrane
Answer: Ab
Textbook AReference: APharmacokinetic AFactors ADetermining ADrug AAction
9. First-pass Ametabolism Aoccurs Awith Aorally Aadministered Adrugs Abecause
a. their Aabsorption Ais Aslowed Aby Afood.
b. drugs Aabsorbed Ainto Athe Abloodstream Afrom Athe Astomach Ago Ato Athe Aliver
Aon Athe Away AtoAgeneral Acirculation.
c. drugs Amust Afirst Asurvive Athe Aacidic Aenvironment Aof Athe Astomach.
d. salivary Aenzymes Ain Athe Amouth Abegin Athe Aprocess Aof Ametabolism.
Answer: Ab
Textbook AReference: APharmacokinetic AFactors ADetermining ADrug AAction
10. Toxic Asubstances Ain Athe Ablood Atrigger Aa Avomiting Aresponse Aby Aactivating Athe
a. blood–brain Abarrier.
b. choroid Aplexus.
c. area Apostrema.
d. median Aeminence.
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, Answer: Ac
Textbook AReference: APharmacokinetic AFactors ADetermining ADrug AAction
11. Drugs Aadministered A_ have Athe Amost Arapid Aonset Aof Aaction.
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer: Ad
Textbook AReference: APharmacokinetic AFactors ADetermining ADrug AAction
12. Ionization Aof Aa Adrug Adepends Aon Athe of Athe Asolution Aand Athe of
AtheAdrug.
a. pH; ApKa
b. pKa; ApH
c. concentration; Alipid Asolubility
d. pH; Aconcentration
Answer: Aa
Textbook AReference: APharmacokinetic AFactors ADetermining ADrug AAction
13. The Aabsorption Aof Aa Adrug Adepends Aon Aall Aof Athe Afollowing Aexcept
a. lipid Asolubility.
b. ionization.
c. body Atemperature.
d. the Aconcentration Aof Athe Adrug.
Answer: Ac
Textbook AReference: APharmacokinetic AFactors ADetermining ADrug AAction
14. Drugs Athat Aare should Abe Aavoided Aby Awomen Aof Achildbearing Aage.
a. teratogenic
b. able Ato Across Athe Aplacental Abarrier
c. psychoactive
d. highly Alipid-soluble
Answer: Aa
Textbook AReference: APharmacokinetic AFactors ADetermining ADrug AAction
15. Agents Athat Ainduce Adevelopmental Aabnormalities Ain Aa Afetus Aare Aknown Aas
a. psychoactive Adrugs.
b. illicit Adrugs.
c. teratogens.
d. placental Adrugs.
Answer: Ac
Textbook AReference: APharmacokinetic AFactors ADetermining ADrug AAction
16. Depot Abinding Ais Asaid Ato Aoccur Awhen Adrugs
a. bind Ato Atheir Atarget Asites.
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