block the gastric H,K-ATPase, inhibiting gastric acid secretion. This effect enables healing of
peptic ulcers, gastroesophageal reflux disease (GERD), Barrett's esophagus, and Zollinger-
Ellison syndrome, as well as the eradication of H-pylori as part of combination regimens.
Action of Proton Pump Inhibitors
Replacement for digestive enzymes Pancrelipase/pancrease
IBS-C, chronic/severe constipation, GI perforation, ischemic colitis, Crohn's disease,
diverticulitis, megacolon, chronic or severe constipation Contraindications for alostron
(Lotrinex)
Adverse effects of Metoclopramide (Reglan) CNS effects. BLACK BOX WARNING:
Severe depression.
, Pharmacology Final – SLCC Questions With
Complete Solutions
Block H2 receptors, which reduces the volume of gastric acid and lowers the concentration of
hydrogen ions in the stomach. Action of H2 inhibitors
Action of Filgrastim (Neupogen) Increase neutrophils. Stimulates production of
Neutrophils.
Labs to monitor effectiveness of heparin PTT
inactivating thrombin and preventing the conversion of fibrinogen to fibrin. It also prevents the
formation of a stable fibrin clot in inhibiting the activation of the fibrin stabilizing factor.
Action of Heparin
Dependent on adequate quantities of iron, folic acid, vitamin B12. Factor that promotes
effectiveness of epoetin alfa
Action of alteplase (Activase) binds to the fibrin in a clot and converts the plasminogen
back to plasmin.
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