DPT NUR6521 Adv.Pharmacology - Exam
Elaboration Questions and Answers
|100% Correct|
What is the primary mechanism of action for angiotensin-converting enzyme (ACE) inhibitors in
managing hypertension?
ACE inhibitors block the conversion of angiotensin I to angiotensin II, leading to
va...
DPT NUR6521 Adv.Pharmacology - Exam
Elaboration Questions and Answers
|100% Correct|
What is the primary mechanism of action for angiotensin-converting enzyme (ACE) inhibitors in
managing hypertension?
ACE inhibitors block the conversion of angiotensin I to angiotensin II, leading to
vasodilation and decreased blood pressure.
Explain how metformin improves glycemic control in patients with type 2 diabetes.
Metformin decreases hepatic glucose production and increases insulin sensitivity in
peripheral tissues, resulting in improved glucose uptake and utilization.
What are the common side effects associated with the use of selective serotonin reuptake
inhibitors (SSRIs)?
Common side effects of SSRIs include nausea, headache, sexual dysfunction, insomnia, and
increased anxiety initially.
Describe the role of anticoagulants in the management of thromboembolic disorders.
Anticoagulants prevent the formation of new blood clots and the growth of existing clots by
inhibiting specific clotting factors in the coagulation cascade.
1
,What is the significance of therapeutic drug monitoring (TDM) in patients on anticonvulsant
therapy?
TDM ensures drug levels remain within a therapeutic range to optimize seizure control while
minimizing the risk of toxicity and adverse effects.
Discuss the potential side effects of long-term corticosteroid therapy.
Long-term corticosteroid therapy can lead to weight gain, osteoporosis, increased blood
sugar levels, susceptibility to infections, and adrenal suppression.
What is the primary therapeutic action of beta-blockers in cardiovascular disease?
CoA reductase, thereby reducing the risk of cardiovascular events.
Discuss the potential interactions between NSAIDs and anticoagulant therapy.
NSAIDs can increase the risk of gastrointestinal bleeding when taken with anticoagulants,
necessitating caution and monitoring for adverse effects.
What is the clinical significance of the half-life of a medication?
The half-life of a medication informs dosing frequency and helps predict how long a drug
will remain active in the body, influencing therapeutic management.
3
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