Thiazide diuretics PEARLs - help with bone loss in post-menopausal women
- can exacerbate gout or cause acute attack
Thiazide diuretics education Educate on high-K diet, signs of electrolyte imbalance
Loop diuretics MOA Acts on ascending loop of Heinle to block reabsorption of NaCl
while also excreting K
, PC707 Module 4 – Cardiac Exam Questions
And Complete Answers
Loop diuretics side effects Hyponatremia, hypochloremia, hypoKalemia, hyperglycemia,
hyperuricemia
Loop diuretic BBW Can cause profound diuresis in high doses - resulting in severe
dehydration and electrolyte imbalances
Loop diuretic PEARL Can be ototoxic
Aldosterone receptor antagonists MOA Blocks aldosterone in distal nephron - retaining K
and excreting Na
Aldosterone receptor antagonists example Spironolactone
Aldosterone receptor antagonist Side effects Hyperkalemia, anti-androgenic effects (post-
menopausal bleeding, ED), gynecomastia
Aldosterone receptor antagonist BBW Tumorigenesis in rats with chronic use
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