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PC707 Module 4 Exam Questions And Complete Answers
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PC707 Module 4 Exam Questions And Complete Answers What can Thiazide Diuretics Enhance the toxic or adverse effects of? Cardiac glycosides like Digoxin Thiazide Diuretic Special Considerations May help with bone loss in post-menopausal women On the Beers list and may be inappropriate for t...

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  • October 13, 2024
  • 64
  • 2024/2025
  • Exam (elaborations)
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PC707 Module 4 Exam Questions And
Complete Answers

What can Thiazide Diuretics Enhance the toxic or adverse effects of? Cardiac glycosides

like Digoxin




Thiazide Diuretic Special Considerations May help with bone loss in post-menopausal

women




On the Beers list and may be inappropriate for those over 65, as there's a potential for SIADH

and hyponatremia. You must monitor their sodium levels.




Thiazide Diuretic Monitoring Serum electrolytes and renal function, BP, fluid status,

weight, and gout.




Thiazide Diuretics in Black Patients Recommended for Black adults with HTN but

without HF or CKD, including those with DM. This should be the initial treatment, or a calcium

channel blocker.




Loop Diuretic Examples Furosemide (Lasix)

, PC707 Module 4 Exam Questions And
Complete Answers
Loop Diuretic Indications Pulmonary edema, edema of cardiac, hepatic, or renal origin,

HTN that doesn't respond to other diuretic classes




Furosemide (Lasix) MOA Blocks the reabsorption of Na and Cl in the ascending limb of

the loop of Henle




Furosemide (Lasix) Risks · Hypokalemia,


· hyponatremia,

· hypochloremia, [Dehydration]

· hyperuricemia [gout],

· hyperglycemia [DM],

· hypomagnesaemia

· hypercalcemia,

· ↑ LDL/total chol, triglycerides &

· ↓HDL




Postural hypotension

, PC707 Module 4 Exam Questions And
Complete Answers
Furosemide (Lasix) Drug-to-Drug Interactions D2D interactions:


(Digoxin, lithium, ototoxic drugs)

· Enhance the adverse/toxic effects of Digoxin, decrease

lithium levels)

· NSAIDS may decrease the effects of loop diuretics.

· Ototoxicity (transient with furosemide; irreversible with ethacrynic acid)-see details about risk

in textbook and Lexicomb




Furosemide (Lasix) Cardiac Considerations Lasix has a Risk of TdP Under Certain

Conditions - hypokalemia, overdose




Furosemide (Lasix) BBW Furosemide is a potent diuretic that, if given in excessive

amounts, can lead to a profound diuresis with water and electrolyte depletion.




Furosemide (Lasix) Special Considerations Monitor electrolytes, renal function, BP, fluid

status, and weight regularly.




Add PO (oral) KCl when indicated.

, PC707 Module 4 Exam Questions And
Complete Answers

Educate slow transition from lying > to sitting > to standing




Furosemide (Lasix) & the Beer's Criteria Use diuretics with caution due to their potential

to cause or exacerbate syndrome of inappropriate antidiuretic hormone secretion (SIADH) or

hyponatremia; monitor sodium closely with initiation or dosage adjustments in older adults.




Aldosterone Receptor Antagonists / Potassium-Sparing Diuretics Examples

Spironolactone (Aldactone)


(aldosterone antagonist)




Triamterene (Dyrenium) or Amiloride

(non-aldosterone antagonists)




Aldosterone Receptor Antagonists / Potassium-Sparing Diuretics Indication HTN, edema,

HF

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