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Ch 17 Concept Check questions well answered to pass
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Ch 17 Concept Check questions well answered to pass
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Ch 17 Concept CheckWhich of the following statements regarding the three types of cytoskeletal filaments in eukaryotic cells
is FALSE?
A. Kinesins and dynein motor proteins use actin microfilaments to transport cellular cargo.
B. Intermediate filaments are the only type of cytoskeletal filament not used as tracks by motor proteins.
C. Microfilaments are composed of actin and contribute to the shape and organization of the plasma
membrane.
D. Microtubules are polymers of the protein tubulin and are the basis of the mitotic spindle. - correct
answer ✔✔A. Kinesins and dynein motor proteins use actin microfilaments to transport cellular cargo.
Which of the following statements regarding actin is NOT correct?
A. At the (+) end of an actin polymer, the ATP-binding cleft is exposed.
B. Actin cross-linking proteins are responsible for the formation of actin bundles and networks.
C. Actin is itself an ATPase.
D. Actin exists in a globular form, G-actin, and as a filamentous polymer, F-actin. - correct answer ✔✔A.
At the (+) end of an actin polymer, the ATP-binding cleft is exposed.
Which of the following statements regarding actin assembly in vitro is FALSE?
A. The addition of ATP-G-actin at the (+) end is 10 times faster than at the (-) end.
B. During the steady-state phase, the concentrations of F-actin and G-actin are in equilibrium, and no
addition to F-actin filaments occurs.
C. Large quantities of G-actin can be purified without filament formation as long as the buffer contains
low levels of cations.
D. Ultracentrifugation can sediment F-actin but not G-actin. - correct answer ✔✔B. During the steady-
state phase, the concentrations of F-actin and G-actin are in equilibrium, and no addition to F-actin
filaments occurs.
Which of the following statements is FALSE?
A. The actin filament has a gradient of actin bound to ATP, actin bound to ADP-Pi and actin bound to ADP.
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