CSO EXAM TEST BANK LATEST REAL EXAM 250
QUESTIONS AND CORRET ANSWERS WITH RATIONALES
(DETAILED ANSWERS) |ALREADY GRADED A+
Ageusia - ANSWER: Loss or absence of the sense of taste
Allogenic marrow transplantation - ANSWER: Transfer of marrow from donor to
another person who is not genetically identical
Antineoplastic agents - ANSWER: Chemical agents (cytotoxics, immuniologic
preparations, hormones) or meds used to prevent the development, maturation or
spread of neoplastic cells
antioxidants - ANSWER: molecules (ie. vitamins) that blcok action of activated
oxygen molecules (free radicals) that can demage cells
antologous marrow transplantation - ANSWER: transfer of marrow from the pt's own
tissue (from hematopietic stem cells)
cancer cachexia - ANSWER: wt loss, anorexia, wasting, immunosuppression, altered
BMR, abnormalitis in fluid & energy metabolism, lessening of the body's fat & muscle
stores that accompanies advanced CA even with adequate nutrition.
carcinogen - ANSWER: an agent (physical, chemical, or viral) that induces CA
carcinogenesis - ANSWER: the origin or development of CA, a multistage, biological
process that proceeds on a continuum but is often described in stages of initiation,
promotion and progression
cytokines - ANSWER: protein mediators produced by inflammatory cells in response
to exogenous stimuli, produce metabolic changes & wating
dysgeusia - ANSWER: impaired taste
graft-versus-host disease (GVHD) - ANSWER: a dz caused by the immune response of
histoincompatible, immunocompetent donor cells against the tissues of an
immunoincompetent host; an immuniologic reaction of allogeneic donor cells (graft)
reacting against the pt (host) tissues
evidenced by icterus & abnormal liver functions, severe /secretory diarrhea - may
need total bowel rest --> isomotic, low residue, lactose-free diet --> solids with low
lactose, fiber, fat & acideity, gastric irritants --> regular diet
- usually 3 onths after transplant (but may be 7-10 days post)
hypogeusia - ANSWER: decreased taste acuity
, initiation - ANSWER: the initial stage of tumorigenesis, involving transformation of
cellular DNA
malignant neoplasm - ANSWER: mass of CA cells that invades surrounding tissues or
spreads to distant areas of body
metastasis - ANSWER: growth of malignant tissue that spreads to surrounding tissue
or organs
myelosuppression - ANSWER: suppression of bone marrow cell production
neutropenia - ANSWER: a reduction of WBC (neutrophils) that can be caused by
chemo or XRT, results in increased susceptibility to life-threatening infections
pancytopenia - ANSWER: a reduction in all cellular elements of the blood
phytochemicals - ANSWER: nonutritive compounds in plants though to influence the
process of tumorigenesis
progression - ANSWER: the phase in which tumor cells aggregate, grow
autonomously and form benign tumors that eventually lead to malignant phenotype
with the capacity for tissue invasion & mets
Promotion - ANSWER: The stage of tumorigenesis in which initiated cells are
activated by a promoting agent to multiply and form a discrete tumor
radiation-induced enteritis - ANSWER: a condition of inflammation that can occur
after XRT to the GI tract & that leads to diarrhea & malabsorption
staging - ANSWER: a classification system known as TNM that is used to identify the
"extent" of the tumor: its size, the degree of growth & spread; T - size of tumor, N-
degree of spread to lymph nodes; M- presence of mets
Tumor necrosis factor - ANSWER: (cachectin, interluckin-1, interleukin-6, interferon-
y); a hormone-like protein that releases fat from fat stores, reduces the
concentration of enzymes required for the production and storage of fat & induces a
stage of anorexia
veno-occlusive disease (VOD) - ANSWER: - transplant related complication
- a symptomatic occlusion of the small hepatic venules caused by hepatotoxins &
XRT; may resolve after removal of the offending agent or may progress to portal HTN
& liver failure
- 1-3 wks post transplant
-hepatomegaly, ascites, jaundice, hepatic failure, encephalopathy & multi-organ
failure
Xerostomia - ANSWER: mouth dryness
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