Exam (elaborations)
2024 NAPLEX EXAM WITH CORRECT ANSWERS
- Course
- Institution
2024 NAPLEX EXAM WITH CORRECT ANSWERS
[Show more]
Content preview
2024 NAPLEX EXAM WITHCORRECT ANSWERS
Key drugs that can cause hypothyroidism - CORRECT-ANSWERS"I TALC"
Interferons
Tyrosine Kinase Inhibitors
Amiodarone
Lithium
Carbamazepine
Conditions: Hashimoto's disease
Levothyroxine IV:PO - CORRECT-ANSWERS0.75:1 (IV:PO)
Full replacement dose levothyroxine - CORRECT-ANSWERS1.6 mcg/kg/day
(IBW)
If known CAD: start with 12.5-25 mcg daily
Schizophrenia - CORRECT-ANSWERSNegative s/sx: loss of interest, lack of
emotion (apathy), inability to plan/carry out activities, social withdrawal,
poor hygiene, loss of motivation (avolition), lack of speech (alogia)
Positive s/sx:
Hallucinations
Delusions
Disorganized thinking/behavior
Difficulty paying attention
Primarily involved DA, 5-HT, glutamine
Medication/recreational drugs that can cause psychotic sx - CORRECT-
ANSWERSAnticholinergics
Dextromethorphan
DA/DA-agonists
Interferons
Stimulants
Systemic steroids
Illicit/recreational substances: bath salts, cannabis, cocaine,
LSD/hallucinogenics, methamphetamine/ice/crystal, PCP
,first generation antipsychotics - CORRECT-ANSWERSLow-potency:
chlorpromazine, thioridazine
- inc sedation, dec EPS
Mid-potency: loxapine, perphenazine
High-potency: haloperidol (haldol), fluphenazine, thiothixene, trifluoperazine
- dec sedation, inc EPS
BBW: inc risk of death in elderly patients with dementia-related psychosis
- thioridazine: QT prolongation
Warnings: QT prolongation, orthostasis/falls, anticholinergic effects, CNS
depression, EPS, hyperprolactinemia, neuroleptic malignant syndrome
(NMS), blood dycrasias
AEs: sedation, dizziness, anticholinergic effects, EPS
- can give anticholinergic to limit/avoid painful dystonic rxns
Second generation antipsychotics (SGAs) - CORRECT-ANSWERSAripiprazole
(Abilify)
Clozapine (Clozaril)
Lurasidone (Latuda)
Olanzapine (zyprexa)
Paliperidone (Invega)
Quetiapine (Seroquel)
Risperidone (Risperdal)
Ziprasidone (Geodon)
Asenapine (Saphris, Secuado)
Brexpiprazole (Rexulti)
Cariprazine (Vraylar)
Aripiprazole (Abilify) - CORRECT-ANSWERSAbilify maintena - IM suspension,
monthly
Aristada- IM suspension, give every 4-8 weeks
Akathisia, activating
Lower risk of weight gain, some QT prolongation, EPS (in children)
*also approved for irritability with autism and Tourette disorder
Clozapine (Clozaril) - CORRECT-ANSWERSNo sooner than 3rd line due to
severe side effect potential: REMS
,BBW: neutropenia/agranulocytosis (REMS), myocarditis/cardiomyopathy,
seizures
AEs: Agranulocytosis, seizures, constipation, metabolic syndrome,
hypersalivation
*to start tx, baseline ANC must be >/= 1500/mm3; check ANC weekly x6
months, then every 2 weeks x6 months, then monthly; stop if ANC <
1000/mm3
Lurasidone (Latuda) - CORRECT-ANSWERSCI: use with strong CYP3A4
inducers/inhibitors
AE: somnolence, EPS, nausea
Risk of metabolic syndrome, but lower risk than other SGAs
Olanzapine (Zyprexa) - CORRECT-ANSWERSIM injection: acute agitation
BBW: Relprevv suspension lasts 2-4 weeks, restricted use; REMS - monitor
for 3 hours post injection
AEs: somnolence, metabolic syndrome
Paliperidone (Invega) - CORRECT-ANSWERSInvega Sustenna: IM injection,
monthly
Invega Trinza: IM injection, every 3 months
Invega Hafyera: IM injection, every 6 months
AEs: inc prolactin, EPS (esp at higher doses), metabolic syndrome
*active metabolite of risperidone
Quetiapine (Seroquel) - CORRECT-ANSWERSAEs: somnolence, metabolic
syndrome
Low EPS risk, often used for psychosis in parkinson disease
Take XR at night, without food or with a light meal
Risperidone (Risperdal) - CORRECT-ANSWERSRisperdal consta: IM injection,
give every 2 weeks
*also approved for irritability associated with autism
AEs: inc prolactin, EPS (esp at higher doses), metabolic syndrome
, Ziprasodone (Geodon) - CORRECT-ANSWERSTake with food
Geodon IM: acute injection
CI: QT prolongation - do not use with QT risk
Asenapine (Saphris) - CORRECT-ANSWERSNo food/drink for 10 minutes after
dose (SL tab)
AEs: somnolence, tongue numbness
AP if cardiac/QT risk - CORRECT-ANSWERSDO NOT choose QT-prolonging
drug like ziprasidone, haloperidol, thioridazine, or chlorpromazine
BBW: thioridazine, ziprasidone
AP if hx of movement disorder - CORRECT-ANSWERSQuetiapine preferred
AP if overweight/metabolic risk - CORRECT-ANSWERSlower metabolic risk
with aripiprazole, ziprasidone, lurasidone, and asenapine
Psychosis in parkinson disease - CORRECT-ANSWERSCommonly, quetiapine
used; less EPS
Pimavanserin (Nuplazid): does not affect DA receptors
Treatment for tardive dyskinesia - CORRECT-ANSWERSValbenazine:
Somnolence
Deutetrabenazine
- CI: hepatic impairment
- warnings: somnolence
Neuroleptic Malignant Syndrome (NMS) - CORRECT-ANSWERSDue to D2
blockade
Signs: hyperthermia, extreme muscle rigidity, mental status changes,
tachycardia/tachypnea/BP changes
- inc CPK/WBCs
STOP antipsychotic and provide supportive care
- cooled IV fluids
- relax muscles: benzos, dantrolene, DA agonist
Bipolar 1 disorder - CORRECT-ANSWERSAt least one episode of mania, and
usually bouts of intense depression
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller Elitaa. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $32.99. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
72042 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now