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MARYVILLE UNIVERSITY PHARMACOLOGY NURS-615 EXAM 2
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MARYVILLE UNIVERSITY PHARMACOLOGY NURS-615 EXAM 2
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MARYVILLE UNIVERSITY PHARMACOLOGY NURS-615EXAM 2
How does carbamazepine work? - Answers-Works by decreasing nerve impulses that
cause seizures and pain
How often should carbamazepine lab values be monitored? What labs? - Answers-CBC
q 3-4 months
What anti-seizure med auto induces metabolism? - Answers-Carbamazepine
What medication decreases the production of RBCs, WBCs, and platelets? - Answers-
Carbamazepine
What medication affects Lamictal? - Answers-OCPs decrease the effects of this drug, so
the dose must be doubled
Can valproate (Depakote) be used during pregnancy? - Answers-It is a known
teratogen. If needed, must be used after 1st trimester.
What must be ruled out in patients before starting an anti-depressant? - Answers-
hypothyroidism
Anti-depressant that is to be used with caution in cardiac patients due to behaving like
class 1 anti-arrythmics? - Answers-TCAs
TCA side effects are mainly of what type? - Answers-Anti-cholinergic
What is a first-line antidepressant in children? - Answers-fluoxetine (Prozac)
How do you discontinue an SSRI? - Answers-Taper by reducing the dose by 50% for 3-
4 days
When are MAOIs effective? - Answers-In atypical depression or Parkinson's
Why are MAOIs reserved for last line of treatment? - Answers-Lethal drug interactions
and food interactions
How long before starting a new antidepressant after MAOIs? - Answers-At least 2
weeks to clear it from system
What are high tyramine foods and when are they contraindicated? - Answers-
Fermented foods; aged cheese, wine alcohol
Contraindicated with MAOI use
, Important drug interaction and side effect with MAOIs? - Answers-Avoid other serotonin
drugs and watch for hypertensive crisis
What anti-depressant may have sleep issues if taken at night? - Answers-fluoxetine
(Prozac) (SSRI)
How do SSRIs work? - Answers-They block the reuptake of serotonin at the synaptic
cleft so there is more serotonin around
How are sexual side effects linked to SSRIs? - Answers-Sexual side effects may start
after 1 month; especially common in Paxil
How long does it take for SSRIs to work? - Answers-2-6 weeks; usually within 4 weeks;
some symptoms may improve within 1 to 2 weeks
What medication is a seroternergic 5-ht receptor partial agonist (partial alpha 1 receptor
agonist)? - Answers-buspirone (Buspar)
What is carbamazepine half-life? - Answers-Single dose: 30 hours
Multiple dose: 15 hours
What is a great risk of seizure potential while taking anti-seizure medications? -
Answers-Stopping the medication abruptly.
What type of medication is topiramate (Topamax)? - Answers-Anti-seizure med
What does topiramate cause? - Answers-Electrolyte imbalance -- hyperchloremic
metabolic acidosis
What are adverse effects of topiramate? - Answers-Weight loss, high temperature, and
inability to sweat
What is special about buspirone (Buspar)? - Answers-It has both anti-anxiety and anti-
depressant effects.
How is treatment with buspirone (Buspar) usually conducted? - Answers-Can be
combined with an SSRI to treat patients with agitated or anxious depression
Benzodiazepines affect what neurotransmitter and how? - Answers-Increases the
effects of GABA
What medications results in a sedative, hypnotic, anxiolytic, and muscle relaxer effect? -
Answers-Benzodiazepines
What anxiolytic has the greatest risk for dependence and resistance? - Answers-
alprazolam (Xanax)
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