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Summary USMLE Step 3 Review Exam Study Gide (Latest Update 2024)

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USMLE Step 3 Review Exam Study Gide (Latest Update 2024)

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  • October 10, 2024
  • 150
  • 2024/2025
  • Summary
  • USMLE Step 3 Revi
  • USMLE Step 3 Revi
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Allivia
USMLE Step 3 Review Exam Study Gide
(Latest Update 2024)
Tx of IBS - Correct Answer ✅ Best initial therapy: *Fiber*



If fiber fails: Antispasmodic/anticholinergic agents.

First line:

1. Dicyclomine

2. Hyoscyamine



Secondline:

1. TCA's (amitriptyline)



CCS, What test should you order for IBS? - Correct Answer
✅ 1. Stool: stool guiac, leukocytes, cultures, ova & parasites.

2. Colonoscopy

3. Abdominal CT scan



Umbilical hernia in newborns is associated with? - Correct
Answer ✅ Congenital hypothyroidism



Screen with TSH (you should screen for TSH anyway)

,USMLE Step 3 Review Exam Study Gide
(Latest Update 2024)

What three metabolic conditions do most states require
newborn screening? - Correct Answer ✅ 1. Phenylketonuria

2. Galactosemia

3. Hypothyroidism



Antibiotics of choice in IBD - Correct Answer ✅
Ciprofloxacin + Metrodinazole (they have some kind of
immune modulatory effect)



Middle-aged woman with itching and xanthelesmas = primary
biliary cirrhosis. What is the best initial test, and the most
accurate test? - Correct Answer ✅ Initial: elevated ALP,
normal bilirubin



Accurate: antimitochondrial antibodies

Liver Biopsy



Antimitochondrial antibodies? - Correct Answer ✅ Primary
biliary cirrhosis

,USMLE Step 3 Review Exam Study Gide
(Latest Update 2024)

Antismooth muscle antibody? - Correct Answer ✅ Primary
sclerosing cholangitis



What condition accounts for most causes of primary
sclerosing cholangitis? - Correct Answer ✅ IBD



What is the best initial test for primary sclerosing cholangitis?
Most accurate? - Correct Answer ✅ Initial: elevated ALP,
*elevated bilirubin*



Best: ERCP (beading of biliary system)



Others: antismooth muscle antibody, ANCA positive



Treatment for both primary biliary cirrhosis and primary
sclerosing cholangitis? - Correct Answer ✅ Ursodeoxycholic
acid

, USMLE Step 3 Review Exam Study Gide
(Latest Update 2024)
Young woman with hepatitis with thyroiditis or ITP,
autoimmune hepatitis. Best initial test, and most accurate? -
Correct Answer ✅ Initial: ANA & antismooth muscle
positive



Best: Liver biopsy



Other: liver/kidney microsomL antibody, SPEP (serum protein
electrophoresis) with hypergammaglobulinemia



Best initial test for hemochromatosis - Correct Answer ✅
Serum iron, iron binding capacity (low), ferritin (high)



Most accurate test for hemochromatosis - Correct Answer
✅ MRI of liver + genetic testing for HFe gene mutation



(Spares liver biopsy)



Last two indications for amphotericin - Correct Answer ✅
Cryptococcus and mucormycosis

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