Oncology Certification – chemo Exam
2024 (100% Accurate!!
vesicants - ANSWERbleomycin, carmustine, cisplatin, daunorubicin, doxorubicin, etposide, idarubicin,
melphalan, taxol, vincristine
cisplatin antidote - ANSWERsodium thiosulfate
doxorubicin antidote - ANSWERDexrazoxane
vincristine antidote - ANSWERhyaluronidase
Alkylating agents - ANSWERbusulfan, cytoxan, melphalan, ifosfamide, carmustine; cell cycle non-
specific; affects heme, GI, reproductive
antimetabolites - ANSWERmethotrexate, 5-FU, cytarabine, gemcitabine, fludarabine; cell cycle
specific, affect counts & GI
platinum compounds - ANSWERcisplatin, carboplatin, oxaliplatin; cell cycle non-specific; affects
heme, GI, neuro, and urinary
topoisomerase targeting agents - ANSWERironitecan, anthracyclines (daunorubicin, doxorubicin,
idarubicin)
Microtubule targeting agents - ANSWERvincristine, taxanes (paclitaxel and docetaxel); cell-cycle
specific, affects heme, skin, neuro, reproductive
Chemos likely to cause nausea - ANSWERcarboplatin, carmustine, cisplatin, cytoxan, cytarabine,
doxorubicin, melphalan, MTX
Chemo likely to cause alopecia - ANSWERcytoxan, daunorubicin, doxorubicin, docetaxel, etoposide,
idarubicine, ifosfamide, paclitaxel
bleomycin - ANSWERVESICANT, risk for anaphylaxis (need test dose, emergency meds at bedside),
risk for pulmonary fibrosis and interstitial pneumonitis
busulfan - ANSWERdosing based on blood busulfan levels, dilantin given to prevent seizures, no
tylenol during or 48 hrs after
carboplatin - ANSWERcheck creatinin, renal and ototoxic
carmustine - ANSWERVESICANT, monitor for dizziness and severe nausea
cisplatin - ANSWERVESICANT, nephrotoxic, requires vigorous hydration and lasix to encourage
urinating 100 mL/hr for 24 hrs
cytoxan - ANSWERhigh dose needs daily EKG and UA, risk of hemorrhagic cystitis, need vigorous
hydration, mesna, lasix, void q2hrs; risk of cardiac tamponade
cytarabine - ANSWERhigh doses require cerebellar check, risk of chemical conjunctivitis, use steroid
eye drops