Half-life - ANS the time required for the amount of the drug in the body to decrease by 50%
therapeutic index - ANS ratio of toxic dose to therapeutic dose
Therapeutic response - ANS the intended (beneficial) effect of a drug
first pass effect - ANS The initial metabolism in the liver of a drug absorbed from the
gastrointestinal tract before the drug reaches systemic circulation through the bloodstream.
brand name - ANS name given to a drug by the pharmaceutical company that developed it; also
called a trade name or proprietary name
generic name - ANS legal noncommercial name for a drug
chemical name - ANS The name that describes the chemical composition and molecular
structure of a drug.
drug-drug interactions - ANS when one drug changes the way another drug affects the body
Drug-Food Interactions - ANS Food is known to increase, decrease, or delay drug absorption.
Food can bind with drugs, causing less or slower drug absorption.
Drug-herbal interactions - ANS occur when herbal or dietary supplements increase or decrease
a drugs effects
Hepatotoxicity - ANS liver toxicity
Nephrotoxicity - ANS damage to the kidneys by a toxic substance
Malignant hyperthermia - ANS A hereditary condition of uncontrolled heat production that occurs
when susceptible people receive certain anesthetic drugs.
TREAT WITH Dantrolene!!
Inhibitor - ANS A substance that slows down or stops a chemical reaction
Antagonist - ANS a chemical or drug that binds to receptors in the brain and prevents an agonist
from having a reaction
Agonist - ANS a chemical that binds to a receptor and activates the receptor to produce a
biological response
Bioavailability - ANS A measure of the extent of drug absorption for a given drug and route
(from 0% to 100%).
, Pharmacokinetics - ANS The process by which drugs are absorbed, distributed within the body,
metabolized, and excreted.
Pharmacodynamics - ANS The process by which a medication works on the body.
ADME - ANS Absorption, Distribution, Metabolism, Excretion/Elimination
Teratogenesis - ANS process involved in producing fetal deformities
Parenteral - ANS by injection
Enteral - ANS referring to a route of medication administration that uses the gastrointestinal
tract, such as swallowing a pill
PO
Routes of drug administration - ANS enteral, parenteral, topical
6 rights of medication administration - ANS Right dose, right time, right patient, right route, right
documentation, right medication
Steps of the Nursing Process (ADPIE) - ANS 1. Assessment
2. Diagnosis
3. Planning
4. Implementation
5. Evaluation
ADPIE explained - ANS • Assessment: 1st step, subjective and objective data
• Diagnosis: analysis, formulation of nursing diagnosis
• Planning: prioritizing problems, determining goals, plan of care
• Implementation: nursing action (rather than medical action)
• Evaluating: comparing outcomes, communicate and document findings
Pre, intra, postoperative nursing assessments - ANS
Medication administration nurses role - ANS •Determines medications ordered are correct
•Assesses patient's ability to self-administer
•Determines medication timing
•Administers medications correctly
•Closely monitors effects
•Provides patient teaching
•Does not delegate medication administration to AP
Narcotic preadministration assessment - ANS Recognize misuse, abuse and addiction
Asses location, cause, pain level duration.
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