Blood Banking Immunology Review Questions with complete Solutions 100% Pass
7 views 0 purchase
Course
Blood Bank
Institution
Blood Bank
Blood Banking Immunology Review Questions with complete Solutions 100% Pass
What are blood group antigens? - Answers Most blood group antigens are proteins, glycoproteins, or glycolipids embedded in or protruding from the RBC membrane. Lewis antigens are exception. They are soluble substances in t...
Blood Banking Immunology Review Questions with complete Solutions 100% Pass
What are blood group antigens? - Answers Most blood group antigens are proteins, glycoproteins, or
glycolipids embedded in or protruding from the RBC membrane. Lewis antigens are exception. They are
soluble substances in the plasma that are absorbed from plasma onto the RBC membrane. Antigens are
also known as agglutinogens or immunogens.
List several blood group antigens of low incidence. - Answers Cw, V, Kpa ,Jsa, Lua, M8, Vw, Dia, Wra, and
Cob. These antigens are found in less than 1% of the population.
List several high incidence blood group antigens. - Answers Kpb, k, Jsb, Lub, I, Ge, Tja, Vel, Yta, Dib, Coa,
and U. These antigens are found in more than 99% of the population.
What is the most common pattern of inheritance for blood group genes? - Answers Autosomal
codominant. The genes are inherited equally by males and females and they are always expressed. For
example, if one inherits the A and B genes, both A and B antigens are detected on the RBCs.
Which RBC antigens are not fully expressed at birth? - Answers A, B, I, P1, Lewis and Lutheran.
What is an antibody? - Answers An immunoglobulin that is produced in response to stimulation by a
specific antigen and is capable of combining with the antigen that elicited its production. Antibodies are
also known as agglutinins. They are found in the plasma and serum.
What is an alloantibody? - Answers An antibody to a foreign antigen from someone of the same species.
What is an autoantibody? - Answers An antibody to an antigen that one possesses. Autoantibodies are
usually only produced in disease states.
What is a naturally-occurring antibody? - Answers One that develops without known antigenic stimulus,
for example, anti-A and anti-B.
What is an immune antibody? - Answers One that results from exposure to a foreign red cell antigen
through transfusion or pregnancy.
If an untransfused male has an unexpected alloantibody, what type of antibody must it be? - Answers A
naturally-occurring antibody. An untransfused male has not been exposed to foreign RBC antigens.
What are high-titer, low-avidity blood group antibodies? - Answers Antibodies that cause weak, variable,
and sometimes irreproducible reactions in the antiglobulin phase at high dilutions. They are not clinically
significant. Example include anti-Ch, Rg, JMH, Csa, Kna, McCa, and Yka.
Which immunoglobulin molecules are most frequently encountered in blood making? - Answers IgM and
IgG.
Compare the molecular structure of IgG and IgM and explain how their structure affects their reactivity
in blood bank testing. - Answers IgG is a monomer. Because of its small size, it usually cannot agglutinate
saline suspended RBCs. A potentiating medium or antiglobulin test is required. IgM is a pentamer.
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller TutorJosh. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $7.99. You're not tied to anything after your purchase.
