Exam (elaborations)
NURS 5334 Exam-Questions with Correct Answers/ Verified/ latest Version (2024/2025)
- Course
- Institution
NURS 5334 Exam-Questions with Correct Answers/ Verified/ latest Version (2024/2025)
[Show more]
Content preview
NURS 5334 Exam-Questions with Correct Answers/ Verified/ latestVersion (2024/2025)
Key Elements of a Prescription - ✔✔1) Prescriber Name
2) License Number
3) Contact Information
4) DEA number of prescriber and supervising physician
5) Patient Name
6) Patient DOB
7) Patient Allergies
8) Name of Medication
9) Indication for Medication
10) Strength of Medication
11) Dosing Frequency
12) Number of tablets/capsules to disepense
13) Number of refills
14) SIG or instructions for the prescription (E.g. "Take one tablet by mouth daily")
3 primary reasons for drug monitoring - ✔✔1) determine therapeutic dosage
2) evaluating medication adequacy: desired effect achieved
3) identifying adverse effects: presence of patient harm
Pharmacokinetics - ✔✔Study of drug movement throughout the body
Includes drug metabolism and excretion
Passage across cell membrane
Absorption - ✔✔Drug's movement from site of administration to the blood
,Rate=how soon effects begin
Amount=how intense the effects will be
Rate of absorption depends on - ✔✔rate of dissolution
surface area
blood flow
lipid solubility
pH partitioning
Distribution - ✔✔Drug's movement from blood into interstitial space and then into cells
Metabolism - ✔✔"Biotransformation"
Enzyme mediated alteration of the drug structure
Excretion - ✔✔How drugs and metabolites move out of the body
Elimination - ✔✔combination of metabolism and excretion
Movement of drugs - ✔✔GI Tract/Site of administration-->Blood-->Liver/Kidney/Site of
action/Other Sites-->Bile/Urine-->Outside of body
3 ways for drugs to cross cell membrane - ✔✔1) Channels and pores
2) Transport systems (P-glycoprotein)
3) Direct penetration of the membrane - **Most common**
P-Glycoprotein - ✔✔Transmembrane protein that transports a wide variety of drugs out of
cells
, Liver to Bile; Kidney to Urine, Placenta to Maternal blood; Brain to Blood
Passage of drugs across membrane - ✔✔"Like dissolves like"
cell membrane composition lipid - lipid soluble drugs can cross membrane without help
Must be Non-Ionized to cross from one side to the other
Ions - ✔✔drug will accumulate on side which favors ionization ("pH partitioning or Ion
trapping")
pH dependent ionization - acid (proton donor) ionizes in basic/alkaline media; base (proton
accepter) ionizes in acidic media
quarternary ammonium compounds - contain at least one atom of nitrogen and carry a
positive charge
Factors Affecting Drug Absorption - ✔✔Rate of dissolution
Surface Area
Blood Flow
Lipid Solubility
pH Partitioning
Routes of Administration: Intravenous (IV) - ✔✔Advantages: Instaneous absorption, rapid
onset
Disadvantages: Expensive, invasive, inconvenient
Routes of Administration: Intramuscular (IM) - ✔✔Advantages: Rapid Absorption with water
soluble drugs
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller MikeHarris. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $12.49. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
80562 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now