ACTIVE LEARNING TEMPLATE: Medication
STUDENT NAME _____________________________________
aspirin (acetylsalicylic acid, Acuprin, ASA)
MEDICATION __________________________________________________________________________ REVIEW MODULE CHAPTER ___________
antipyretics, nonopioid analgesics // salicylates
CATEGORY CLASS ______________________________________________________________________
PURPOSE OF MEDICATION
Expected Pharmacological Action Therapeutic Use
Produce analgesia and reduce inflammation Analgesia. Reduction of inflammation.
and fever by inhibiting the production of Reduction of fever. Decreased incidence of
prostaglandins. Decreases platelet transient ischemic attacks and MI
aggregation.
Complications Medication Administration
revention of Myocardial Infarction/Antiplatelet effectsPO (Adults):
EENT: tinnitus. GI: GI BLEEDING, dyspepsia, epigastric distress, 80 – 325 mgonce daily Suspected acute MI-160 mg as soon as
nausea, abdominal pain, anorexia, hepatotoxicity, vomiting. Hemat: MI is suspected.PO (Children): 3– 10 mg/kg/day given once daily
anemia, hemolysis. Derm: rash, urticaria. Misc: allergic reactions (round dose to a convenient amount).Pain/FeverPO, Rect
(Adults): 325– 1000 mg q 4– 6 hr (not to exceed 4 g/day).
including ANAPHYLAXIS and LARYNGEAL EDEMA. Extended- releasetablets—650mgq8hror800mgq12hr.PO, Rect
(Children 2 – 11 yr): 10 – 15 mg/kg/dose q 4 – 6 hr; maximum
dose: 4 g/ day.InflammationPO (Adults): 2.4 g/day initially;
increased to maintenance dose of 3.6 – 5.4 g/day in divided
doses (up to 7.8 g/day for acute rheumatic fever).PO (Children):
60– 100 mg/kg/day in divided doses (up to 130 mg/kg/day for
acute rheumatic fever).Prevention of Transient Ischemic
AttacksPO (Adults): 50 – 325 mg once daily.
Contraindications/Precautions
Contraindicated in: Hypersensitivity to aspirin or other salicylates;
Cross-sensitivity with other NSAIDs may exist (less with nonaspirin
salicylates); Bleeding disorders or thrombocytopenia; Pedi: May Nursing Interventions
increase risk of Reye’ s syndrome in children or adolescents with
Patients who have asthma, allergies, and
viral infections. nasal polyps or who are allergic to
tartrazine are at an increased risk for
developing hypersensitivity reactions.Pain:
Assess pain and limitation of movement;
note type, location, and intensity before
Interactions and at the peak (see Time/Action Profile)
after administration.Fever: Assess fever
May increase the risk of bleeding with warfarin, heparin, heparin-like and note associated signs (diaphoresis,
agents, thrombolytic agents, dipyridamole, ticlopidine, clopidogrel, tachycardia, malaise, chills).
tirofiban, or eptifibatide, although these agents are frequently used
safely in combination and in sequence.Increases anticoagulant effect
and bleeding risk with arnica, chamomile, clove, feverfew, garlic,
ginger, ginkgo, Panax ginseng, and others.
Client Education
Instruct patient to take salicylates with a full glass of water and to
remain in an up- right position for 15 – 30 min after
administration.Advise patient to report tinnitus; unusual bleeding
of gums; bruising; black, tarry stools; or fever lasting longer than
Evaluation of Medication Effectiveness 3 days.Caution patient to avoid concurrent use of alcohol with
this medication to minimize possible gastric irritation; 3 or more
glasses of alcohol per day may increase risk ofGI bleeding.
Increase in BP. Caution patient to avoid taking concurrently with acetaminophen
or NSAIDs for more than a few days, unless directed by health
Increase in peripheral circulation. care professional to prevent analgesic nephropathy
Increase in urine output
ACTIVE LEARNING TEMPLATES THERAPEUTIC PROCEDURE A7