USMLE Final Competency Certification Study Guide Exam Questions with Certified for Accuracy Answers 2024/2025
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Course
USMLE
Institution
USMLE
USMLE Final Competency Certification Study Guide Exam Questions with Certified for Accuracy Answers 2024/2025
Most common cause of constrictive pericarditis - correct answer tuberculosis
Soap bubble on x-ray - diagnosis? - correct answer giant cell tumor of bone
Spike and dome on EM - ...
Most common cause of primary hyperparathyroidism - correct
answer adenoma
What is the defect in Fabry's disease?
- what substrate accumulates?
- what is fabry's - correct answer deficient alpha-galactosidase
A
- ceramide trihexoside accumulates
- lysosomal storage disease involving dysfunction metabolism of
sphingolipids
Most common cause of glomerulonephritis in adults - correct
answer iga nephropathy (Berger's disease)
Functions of ATP and GTP in protein synthesis - correct answer
ATP - for trna charging (Activation)
GTP - for trna binding to ribosome and translocation (Gripping
and Going places)
, Chloramphenicol - mechanism of action? - correct answer
inhibits 50S peptidyltransferase (which catalyzes peptide bond
formation)
Function of Vibrio cholerae toxin - correct answer activates
Gs, stimulating adenylyl cyclase - increases Cl- in gut and
decreases Na+ absorption
What is the defect in Hurler's syndrome?
- what substrates accumulate? - correct answer deficient
alpha-L-iduronidase
- heparan sulfate and dermatan sulfate accumulates
NB: also called "gargolysm" dwarfism, unique facial features,
hepatosplenomegally
Most common preventable cancer - correct answer lung
cancer
Most common esophageal cancer - correct answer squamous
cell carcinoma
What is the defect in Hunter's syndrome?
- what substrates accumulate?
- what is the inheritance pattern? - correct answer deficient
iduronate sulfatase
- heparan sulfate and dermatan sulfate accumulate
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