PATHOPHYSIOLOGY
THE BIOLOGIC BASIS FOR DISEASE IN ADULTS AND CHILDREN
ia ia ia ia ia ia ia ia
8th Edition
ia
Kathryn L. McCance, Sue E. Huether
ia ia ia ia ia
, 2
ia ia ia
Contents
Chapter 01: Cellular Biology ......................................................................................................................... 4
ia ia ia
Chapter 02: Altered Cellular and Tissue Biology: Environmental Agents .................................................. 18
ia ia ia ia ia ia ia ia
Chapter 03: The Cellular Environment: Fluids and Electrolytes, Acids and Bases ..................................... 31
ia ia ia ia ia ia ia ia ia ia
Chapter 04: Genes and Genetic Diseases ................................................................................................... 44
ia ia ia ia ia
Chapter 05: Genes, Environment-Lifestyle, and Common Diseases .......................................................... 55
ia ia ia ia ia ia
Chapter 06: Epigenetics and Disease .......................................................................................................... 63
ia ia ia ia
Chapter 07: Innate Immunity: Inflammation and Wound Healing............................................................. 68
ia ia ia ia ia ia ia
Chapter 08: Adaptive Immunity ................................................................................................................. 83
ia ia ia
Chapter 09: Alterations in Immunity and Inflammation ............................................................................ 95
ia ia ia ia ia ia
Chapter 10: Infection ................................................................................................................................ 108
ia ia
Chapter 11: Stress and Disease ................................................................................................................ 117
ia ia ia ia
Chapter 12: Cancer Biology....................................................................................................................... 124
ia ia ia
Chapter 13: Cancer Epidemiology............................................................................................................. 137
ia ia ia
Chapter 14: Cancer in Children ................................................................................................................. 143
ia ia ia ia
Chapter 15: Structure and Function of the Neurologic System................................................................ 148
ia ia ia ia ia ia ia ia
Chapter 16: Pain, Temperature Regulation, Sleep, and Sensory Function .............................................. 159
ia ia ia ia ia ia ia ia
Chapter 17: Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function............... 174
ia ia ia ia ia ia ia ia ia ia
Chapter 18: Disorders of the Central and Peripheral Nervous Systems and the Neuromuscular Junction
ia ia ia ia ia ia ia ia ia ia ia ia ia
.................................................................................................................................................................. 188 ia
Chapter 19: Neurobiology of Schizophrenia, Mood Disorders, and Anxiety Disorders ........................... 199
ia ia ia ia ia ia ia ia ia
Chapter 20: Alterations of Neurologic Function in Children..................................................................... 206
ia ia ia ia ia ia ia
Chapter 21: Mechanisms of Hormonal Regulation................................................................................... 213
ia ia ia ia ia
Chapter 22: Alterations of Hormonal Regulation ..................................................................................... 222
ia ia ia ia ia
Chapter 23: Obesity and Disorders of Nutrition ....................................................................................... 234
ia ia ia ia ia ia
Chapter 24: Structure and Function of the Reproductive Systems .......................................................... 239
ia ia ia ia ia ia ia ia
Chapter 25: Alterations of the Female Reproductive System .................................................................. 249
ia ia ia ia ia ia ia
Chapter 26: Alterations of the Male Reproductive System...................................................................... 259
ia ia ia ia ia ia ia
Chapter 27: Sexually Transmitted Infections............................................................................................ 265
ia ia ia ia
Chapter 28: Structure and Function of the Hematologic System............................................................. 273
ia ia ia ia ia ia ia ia
Chapter 29: Alterations of Erythrocytes, Platelets, and Hemostatic Function ......................................... 283
ia ia ia ia ia ia ia ia
, 3
ia ia ia
Chapter 30: Alterations of Leukocyte and Lymphoid Function ................................................................ 293
ia ia ia ia ia ia ia
Chapter 31: Alterations of Hematologic Function in Children.................................................................. 300
ia ia ia ia ia ia ia
Chapter 32: Structure and Function of the Cardiovascular and Lymphatic Systems ............................... 311
ia ia ia ia ia ia ia ia ia ia
Chapter 33: Alterations of Cardiovascular Function ................................................................................. 324
ia ia ia ia ia
Chapter 34: Alterations of Cardiovascular Function in Children .............................................................. 338
ia ia ia ia ia ia ia
Chapter 35: Structure and Function of the Pulmonary System ............................................................... 346
ia ia ia ia ia ia ia ia
Chapter 36: Alterations of Pulmonary Function ....................................................................................... 356
ia ia ia ia ia
Chapter 37: Alterations of Pulmonary Function in Children ..................................................................... 373
ia ia ia ia ia ia ia
Chapter 38: Structure and Function of the Renal and Urologic Systems ................................................. 381
ia ia ia ia ia ia ia ia ia ia
Chapter 39: Alterations of Renal and Urinary Tract Function .................................................................. 391
ia ia ia ia ia ia ia ia
Chapter 40: Alterations of Renal and Urinary Tract Function in Children................................................ 401
ia ia ia ia ia ia ia ia ia ia
Chapter 41: Structure and Function of the Digestive System .................................................................. 409
ia ia ia ia ia ia ia ia
Chapter 42: Alterations of Digestive Function .......................................................................................... 421
ia ia ia ia ia
Chapter 43: Alterations of Digestive Function in Children ....................................................................... 432
ia ia ia ia ia ia ia
Chapter 44: Structure and Function of the Musculoskeletal System ....................................................... 441
ia ia ia ia ia ia ia ia
Chapter 45: Alterations of Musculoskeletal Function .............................................................................. 453
ia ia ia ia ia
Chapter 46: Alterations of Musculoskeletal Function in Children ............................................................ 466
ia ia ia ia ia ia ia
Chapter 47: Structure, Function, and Disorders of the Integument ........................................................ 475
ia ia ia ia ia ia ia ia
Chapter 48: Alterations of the Integument in Children............................................................................ 486
ia ia ia ia ia ia ia
Chapter 49: Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults ................................... 494
ia ia ia ia ia ia ia ia ia ia
Chapter 50: Shock, Multiple Organ Dysfunction Syndrome, and Burns in Children ................................ 502
ia ia ia ia ia ia ia ia ia ia
, Test Bank - Pathophysiology: The Biologic Basis for Disease in Adults and Children (8th)
ia ia ia ia ia ia ia ia ia ia ia ia ia ia ia ia ia i a 4
Chapter 01: Cellular Biology
ia ia ia
MULTIPLE CHOICE ia
1. Which statement best describes the cellular function of metabolic absorption?
ia ia ia ia ia ia ia ia ia
a. Cells can produce proteins. ia ia ia
b. Cells can secrete digestive enzymes. ia ia ia ia
c. Cells can take in and use nutrients. ia ia ia ia ia ia
d. Cells can synthesize fats. ia ia ia
ANS: C ia
In metabolic absorption, all cells take in and use nutrients and other substances from their
ia ia ia ia ia ia ia ia ia ia ia ia ia ia
surroundings. The remaining options are not inclusive in their descriptions of cellular
ia ia ia ia ia ia ia ia ia ia ia ia
metabolicabsorption.
ia ia
PTS: ia ia i a 1 DIF: Cognitive Level: Remembering ia ia
2. Where is most of a cell’s genetic information, including RNA and DNA, contained?
ia ia ia ia ia ia ia ia ia ia ia ia
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Lysosome
ANS: C ia
The nucleus contains the nucleolus, a small dense structure composed largely of RNA, most
ia ia ia ia ia ia ia ia ia ia ia ia ia
ofthe cellular DNA, and the DNA-binding proteins, such as the histones, which regulate its
ia ia ia ia ia ia ia ia ia ia ia ia ia ia ia
activity. The mitochondria are responsible for cellular respiration and energy production.
ia ia ia ia ia ia ia ia ia ia ia
Ribosomes’ chief function is to provide sites for cellular protein synthesis. Lysosomes
ia ia ia ia ia ia ia ia ia ia ia
functionas the intracellular digestive system.
ia ia ia ia ia ia
PTS: ia ia i a 1 DIF: Cognitive Level: Remembering ia ia
3. Which component of the cell produces hydrogen peroxide (H2O2) by using oxygen to
ia ia ia ia ia ia ia ia ia ia ia ia
ia removehydrogen atoms from specific substrates in an oxidative reaction?
ia ia ia ia ia ia ia ia ia
a. Lysosomes
b. Peroxisomes
c. Ribosomes
d. Endosome
ANS: B ia
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller DREAMS. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $18.49. You're not tied to anything after your purchase.
