What does folate deficiency resemble? - answer megaloblastic anemia as seen in B12
deficiency except that neurologic abnormalities are absent
When does megaloblastic anemia of folate deficiency develop? - answer within 4-5
months
When does neural tube closure take place? - answer21-28 days post conception
What is the most common neural tube defect? - answer spina bifida
What is the recommended daily intake of folic acid for nonpregnant women with no
known risk factors for neural tube defect? - answer400 mcg
What medication places women at a higher risk for a neural tube defect-affected
pregnancy? - answer anticonvulsants
What ethnicity is at a higher risk for having babies with congenital neural
malformations? - answerhispanic
What antibiotics should be avoided in pregnancy? - answertetracyclines,
fluoroquinolones, bactrim (in the 1st trimester), macrobid in the last few weeks of
pregnancy
What is 1st line therapy for treating UTI in pregnancy? - answer• Nitrofurantoin
monohydrate/macrocrystals 100 mg orally twice daily for 5-7
days or
• Amoxicillin 500 mg orally twice daily (alternative: 250 mg orally three times
daily) for 5-7 days or
• Amoxicillin-clavulanate 500/125 mg orally twice daily for 3-7 days
(alternative: 250/125 mg orally three times daily for 5-7 days) or
• Cephalexin 500 mg orally twice daily for 3-7 days
What are risk factors for gestational diabetes? - answerobesity, older age, having a
family history of type 2 diabetes or belonging to an ethnic group at increased risk for the
condition (such as Hispanic, Native American, South or East Asian, African American,
or Pacific Islands descent)
Women with gestational diabetes are at higher risk for what? - answergestational htn,
preeclampsia, c/s, and having diabetes later in life
, The offspring of women with gestational diabetes are at increased risk for what? -
answermacrosomia, neonatal hypoglycemia,
hyperbilirubinemia, operative delivery, shoulder dystocia, and birth trauma
Describe ACOGs recommended 2 step approach to dx GD in pregnancy? When is the
test usually performed? - answerfirst screening with the administration of 50 g of an oral
glucose solution followed by a 1-hour venous glucose determination. Those women
meeting or exceeding the screening threshold of > or = 140 undergo a 100-g, 3-hour
diagnostic oral glucose tolerance test (OGTT); at 24-28 weeks
In women in whom GD is diagnosed, what is the blood glucose cutoff? (depending on
community prevalence rates) - answer135-140
What is the recommended initial management of women diagnosed with DM? -
answernutritional counseling by a registered dietitian, if possible, and advice on a
moderate exercise
program.
When is postpartum screening of GD recommended? - answer6-12 weeks postpartum
What percentage of women experience some type of mood disturbance in the
postpartum period? - answer85%
Some women may be abnormally sensitive to changes in the hormonal milieu and may
develop depressive symptoms when treated with what? - answerexogenous estrogen
and progesterone
What screening tool is a 10-item, self-rated questionnaire used extensively for detection
of postpartum depression? - answerThe Edinburgh Postnatal Depression Scale (EPDS)
A score of ___ or more on the EPDS or an affirmative answer on question ____
(presence of suicidal thoughts) requires more thorough evaluation - answer10
What scale is a common, 10-item, clinician-administered evaluation used following a
positive screen, and it accurately differentiates depressed and nondepressed patients,
evaluates severity of disease, and detects changes in symptoms over time - answerThe
Montgomery-Asberg Depression Rating Scale
When do symptoms of postpartum blues peak? When do they usually remit? -
answerDay 4 or 5; 2 weeks
What treatment is indicated for postpartum blues? - answersupport and reassurance
When does postpartum depression usually develop? - answerin the first 4 months, but
can occur in the 1st year
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