Laboratory Animal Exam Questions with Correct Answers
2 views 0 purchase
Course
Laboratory Animal Technician
Institution
Laboratory Animal Technician
Veterinarian Responsibilities - Answer-- provide vet care
- management of facilities
- education of individuals using animals
- assist scientists in selection of animal model
- obtaining and interpreting quality data
- compliance with regulations and policies
Veterinary Technician - Answer-...
Laboratory Animal Exam Questions with
Correct Answers
Veterinarian Responsibilities - Answer-- provide vet care
- management of facilities
- education of individuals using animals
- assist scientists in selection of animal model
- obtaining and interpreting quality data
- compliance with regulations and policies
Veterinary Technician - Answer-work under supervision of vet; provide technical support
- disease detection
- treatment of ill animals
- blood and tissue collection
- sentinel program
- compliance
- technical assistance, surgery, advanced techniques
Sentinel Animal/Program - Answer-- an animal deliberately placed in a particular
environment to detect the presence of an infectious agent, such as a virus
Animals Used in Biomedical Research - Answer-provided advances in medicine and
science
- vaccines
- drugs and antibiotics
- treatment methods
- surgical and diagnostic procedure
Animals Used in Product Safety Testing - Answer-- untested products led to human
deaths
- passage of Food, Drug, and Cosmetic Act
Definition of Lab Animal? - Answer-- any vertebrate animal (e.g., traditional laboratory
animals, agricultural animals, wildlife, and aquatic species) produced for or used in
research, teaching or testing
Animal Use - Answer-- 26 million mice and rats used yearly
- Mice and Rats account for 95% of animals
- dogs, cats and primates account for <1%
What percentage of mice and rats are used for lab animal use? - Answer-95%
What percentage of dogs, cats and primates are used for lab animal use? - Answer-
<1%
,Passage of which law led to product safety testing? - Answer-Food, Drug & Cosmetic
Act
Funding Sources - Answer-- the primary public granting agency for biomedical research
is the NIH (National Institute of Health)
Regulatory Oversight - Answer-- Multiple levels of regulation
* International (CITES)
* Federal (USDA Animal Welfare Act 1966)
* Animal Care Policies
* State
* Voluntary
> Association for Assessment and Accreditation of Laboratory Animal Care
International (AAALAC)
What is the primary publication used by AAALAC for evaluation? - Answer-Guide for the
Care and Use of Laboratory Animals
IACUC - Answer-Institutional Animal Care and Use Committee
- review animal welfare concerns
- has the authority to oversee the "animal program, facilities and procedures"
- focus on humane endpoints and optimal care of animals
- authorized to suspend
activities using animals
- reports directly to the I.O.
Humane Endpoints - Answer-in place to minimize pain and distress as much as
possible
i.e.,
- defined % of weight loss or tumor size
- presence of labored breathing
- inability to ambulate (walk, move about)
What do Protocols include? - Answer-detailed written description of:
- proposed animal care and use
- justifies use of animals
- not a duplication
- staff have adequate training
- alternatives have been considered
Ethical Considerations - Answer-- The 3 R's proposed by Russell and Burch
Replacement
Refinement
Reduction
,Replacement - Answer-- replace with a non-animal alternative
*in vitro methods
*computer based simulators
*using least sentient animal that will enable good data collection (rat vs. dog)
*utilize special rodents, such as nude and transgenic mice
Refinement - Answer-- procedures to lessen pain and distress and enhance animal
well-being
* less invasive procedures
* providing pain relief
* environmental enrichment
* decrease restraint time
* anesthesia
* analgesia
Reduction - Answer-- utilizing the minimal # of animals in a study
What are the 3 R's? - Answer-1. Replacement
2. Refinement
3. Reduction
Prior to use of animals, a protocol must be approved by which committee? - Answer-
IACUC - Institutional Animal Care and Use Committee
Animal Rights definition - Answer-- animals have same equality and protection as
humans
Animal Welfare definition - Answer-- animals can be used but must be treated humanely
- animals physical and psychological well-being is met
Random Source Animals - Answer-- obtain from USDA Class B dealers
* individual owners or breeders
* pounds and animal shelters
- desirable attributes
* genetically diverse, size
* sociable and tractable
- concern
* previous pet
* animal may have been diverted differently than owner intended
Purpose Bred Animals - Answer-- obtained from USDA Class A dealers or privately
owned research colonies
- bred and raised specifically for research
- desirable characteristics
* more genetically similar
* uniquely aged
, * fewer health problems
* accustomed to cage life
Nonhuman Primate Use - Answer-- accounts for <1% of USDA regulated animals
- usage has moral and ethical implications
- should be utilized only when another animal model cannot be used
- chimpanzees
* served an important role in advancing human health (polio and hepatitis B vaccines)
AALAS - Answer-American Association for Laboratory Animal Science
- nonprofit
- promotes education
- certifies trained technicians
ASLAP - Answer-American Society of Laboratory Animal Practitioners
- organization where DVM's can exchange ideas, knowledge and experiences
- spokesperson for laboratory animal practitioners within the AVMA
- encourages training
ACLAM - Answer-American College of Laboratory Animal Medicine
- sponsors annual meetings
- develops educational material
- certification of Veterinary specialists
FBR - Answer-Foundation for Biomedical Research
- promotes public understanding and support for humane and responsible animal
research
- provides info to teachers, students, media, general public about the essential need for
lab animals
ILAR - Answer-Institute for Laboratory Animal Research
- develops guidelines
- responsible for creation and publication of "the Guide"
Who published the 3 R's? - Answer-Russell and Burch in 1959
Committee membership of IACUC - Answer-- DVM
- practicing Scientist
- non-scientific background
- public member
According to the AWA, what is the minimum number of IACUC members? - Answer-3
How can animal #'s be reduced? - Answer-- by using computer-based simulators
- employing better statistical methods
- running multiple study groups against the control group(s)
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller lectknancy. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $20.49. You're not tied to anything after your purchase.
