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NR 507: Advanced Pathophysiology Midterm Exam Study Guide with Complete Solutions

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NR 507: Advanced Pathophysiology Midterm Exam Study Guide with Complete Solutions Asthma - Answer-Chronic disease due to bronchoconstriction and an excessive inflammatory response in the bronchioles What are 5 s/s of asthma - Answer-coughing wheezing shortness of breath rapid breathing che...

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  • October 6, 2024
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NR 507: Advanced Pathophysiology
Midterm Exam Study Guide with
Complete Solutions

Asthma - Answer✔✔-Chronic disease due to bronchoconstriction and an excessive inflammatory

response in the bronchioles


What are 5 s/s of asthma - Answer✔✔-coughing


wheezing


shortness of breath


rapid breathing


chest tightness


Pathophysiology of asthma (5) - Answer✔✔--airway inflammation, bronchial hyper-reactivity and

smooth muscle spasm


-excess mucus production and accumulation


-hypertrophy of bronchial smooth muscle


-airflow obstruction


-decreased alveolar ventilation


Bronchioles - Answer✔✔-smaller passageways that originate from the bronchi that become the alveoli


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FIRST PUBLISH SEPTEMBER 2024


3 layers of the bronchioles - Answer✔✔-innermost layer


middle layer - lamina propria


outermost layer


lamina propria - Answer✔✔-the middle layer of the bronchioles


structure of the lamina propria - Answer✔✔-embedded with connective tissue cells and immune cells


purpose of the lamina propria - Answer✔✔-white blood cells are present to help protect the airways


How does the lamina propria effect the lungs in regards to asthma - Answer✔✔-the WBCs protective

feature goes into overdrive causing an inflammatory response that damages host tissue


What does the innermost layer of the bronchioles contain - Answer✔✔-columnar epithelial ells and

mucus producing goblet cells


What does the outermost layer of the bronchioles contain - Answer✔✔-smooth muscle cells


what does the outermost layer of the bronchioles do - Answer✔✔-control the airways ability to constrict

and dilate


alveolar hyperinflation - Answer✔✔-When air is unable to move out of the alveolar like it should due to

bronchial walls collapsing around possible mucus plug thus trapping air inside


how does hyperinflation occur? - Answer✔✔-the ongoing inflammatory process of asthma produces

mucus and pus plug that the bronchial walls collapse around


Effect of hyperinflation of the alveolar - Answer✔✔--expanded thorax and hypercapnia (retention of

CO2)

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FIRST PUBLISH SEPTEMBER 2024


- respiratory acidosis


What are two anticholinergic drugs used for asthma - Answer✔✔-tiotropium and ipratropium


What do anticholinergics do in the lungs? - Answer✔✔-These drugs block the effects of the

parasympathetic nervous system


- increasing bronchodilation


MOA of anticholinergic drugs for asthma - Answer✔✔-the parasympathetic system is stimulated by the

vagal nerve to release acetylcholine which binds to the cholinergic receptors of the respiratory tract to

cause bronchial constriction = decreased airflow




- blocking the cholinergic receptors prevents acetylcholine binding preventing the bronchial constriction


bronchitis - Answer✔✔-inflammation of the bronchial tubes


3 characteristics of bronchitis - Answer✔✔-bronchial inflammation


hypersecretion of mucus


chronic productive cough for at least 3 consecutive months for at least 2 successive years


Perfusion - Answer✔✔-The supply of oxygen to and removal of wastes from the cells and tissues of the

body as a result of the flow of blood through the capillaries.


results of chronic bronchitis/ low perfusion - Answer✔✔-cyanosis


right to left shunting



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