HSC 411 Final Test Questions and Answers All Correct
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Course
HSC 411
Institution
HSC 411
HSC 411 Final Test Questions and Answers All Correct
Which of the following are true with regard to Major Histocompatibility Complexes? - Answer- A. MHC protein cell surface receptors are coded for on Chromosome 6
B. MHC I molecules offer evidence of cell mutations or viral invaded cells
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HSC 411 Final Test Questions and
Answers All Correct
Which of the following are true with regard to Major Histocompatibility Complexes? -
Answer- A. MHC protein cell surface receptors are coded for on Chromosome 6
B. MHC I molecules offer evidence of cell mutations or viral invaded cells
C. MHC II proteins are displayed on the surface of certain phagocytes after engulfment
of extracellular molecules
Macrophages play a central role in immunity by acting as antigen presenting cells.
Arrange the following in the correct order to describe the sequence of events occurring
in this response: - Answer- 1. Recognition or the pathogen
2. Engulfment via endocytosis
3. Intracellular killing via lysosomal action
4. Display foreign peptides on cell membrane of APC
5. MHC II/ CD4 interaction
6. Macrophage release of IL-1
T or F Besides producing a temporary increase in circulating antibodies for the
pathogen, a vaccine will also boost the memory B population. - Answer- true
Which statement is correct with regards to the complement system? - Answer-
complement proteins are activated in a cascade that is initiated by the Ag/Ab complex
Helper T lymphocytes: (select all that apply) - Answer- A. Have CD4 surface receptors
B. Direct the immune response through cytokine release
C. Recognize (bind with) MHC class II antigens
D. Release interferon to stimulate macrophages
Plasma cells (select all that apply) - Answer- Produce antigen specific antibodies
Which of the following is INCORRECTLY matched: - Answer- Recognizes (binds with)
viral infected - Helper T cells
The "Molecular Mimicry" theory involves: - Answer- An immune response directed
against self antigens after the immune system has responded to foreign antigens with
similar molecular structure.
, A 25-year-old woman has been feeling tired for the past 4 weeks. She says she "aches
all over" (particularly her shoulders and hips). Physical examination reveals only a facial
erythematic rash. Laboratory findings include abnormal protein in the urine, normal liver
enzymes and a near normal CBC. Which of the following additional laboratory tests
would be most useful to perform in her case for a more definitive diagnosis? - Answer-
blood test for ANAs
Although the etiology of autoimmune diseases is idiopathic we have many suspicions
about factors that increase an individuals risk of developing these disorders. Risk
factors include all but which of the following: - Answer- advanced age
Which cells stimulate both humoral and cell mediated arms of the immune response? -
Answer- helper t cells
During initial exposure to the allergen: - Answer- A. the patient is asymptomatic
B. IgEs are produced
C. Mast cells become sensitized
A 28 year old woman presents to her doctor with a 1 week history of tingling, numbness
and clumsiness of both hands. She is also experiencing numbness from the umbilicus
to the axillae. Four months earlier, following a lengthy viral infection, she had
experienced paresthesia (loss of feeling) in the feet, numbness from the waist
downwards and 'burning' pains behind the right ear.
What cells are likely being affected by the inappropriate immune response? - Answer-
oligodendrocytes
Although Lupus is difficult to diagnose, which of the following can be used to support a
diagnosis of SLE (select all that apply) - Answer- A. positive for ANA
B. proteinuria
C. butterfly rash
D. joint swelling
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