2024 NR546 WEEK 2 EXAM WITH
CORRECT ANSWERS
Pharmacokinetics - CORRECT-ANSWERSthe study of what happens to a drug
from the time of administration until the parent drug and all metabolites
leave the body
Pharmacokinetics concepts - CORRECT-ANSWERSabsorption
distribution
metabolism
excretion
During a follow up appointment after 4 weeks, the PMHNP should assess for
the need to add which medication to Ernesto's treatment plan? - CORRECT-
ANSWERSThe nurse should assess for sexual dysfunction and anticipate the
potential need for a phosphodiesterase inhibitor such as sildenafil (Viagra).
-After 4 to 6 weeks, the client should be experiencing full effects of the SSRI,
so the need for a short-term medication like a benzodiazepine or a beta
blocker are not anticipated. St. John's Wort is contraindicated with an SSRI
and can cause serotonin syndrome.
Glu - CORRECT-ANSWERSGlutamate
-amino acid
-excitatory neurotransmitter
-"workhorse" of the brain-can affect almost every neuron in the brain
-affects: energy, memory, learning, neural plasticity
-relay sensory info. and regulate spinal and motor reflexes
-too much: schizophrenia, epilepsy, mania
-receptors: NMDA, AMPA
GABA - CORRECT-ANSWERSinhibitory neurotransmitter
-decrease neuroexcitability across the brain
-"chill", take the edge off stress, help people calm down, relax, destress,
sleep
-to little: may experience anxiety or schizophrenia
-slows down everything, even breathing
-affect executive function and motor coordination, increase risk for accidents
-Increased levels of gamma-aminobutyric acid have a calming effect.
5HT - CORRECT-ANSWERSSerotonin
-help regulate mood
, -makes relaxed, comfortable, decreases stress, regulate sleep, arousal,
libido, aggression, pain perception
NE - CORRECT-ANSWERSnorepinephrine
-monoamine neurotransmitter
-focus and productivity
-too much due to stress, meds, caffein, stimulants can cause: nervous, antsy,
affect focus
DA - CORRECT-ANSWERSdopamine
-monoamine neurotransmitter
-regulate mood
-associated with executive function, ability to perform well, be organized,
emotional intelligence
-movement and coordination
-to little: lose pleasure, interest, alertness, self-confidence, parkinson's
disease
-to much: schizophrenia and psychosis
-reward center: can lead to addiction
-has own pathways
Ach - CORRECT-ANSWERSacetylcholine
-in CNS: affects arousal, motivation, attention, learning, REM sleep, impacts
sleep, pain perception, memory
-in PNS: makes you sweat and salivate
-link between brain and muscles
-not enough: Alzheimer's, Parkinson's, Schizophrenia
-too much: Depression
-Role in addiction
-Receptors: nicotinic & muscarinic
Histamine (Neurotransmitter) - CORRECT-ANSWERSHistamine impacts
alertness, pain sensation, and inflammatory responses; increased levels
result in depression.
Melatonin (neurotransmitter) - CORRECT-ANSWERSAct at MT1-3 G-protein
coupled receptors
Sleep/wake cycle
insomnia: melatonin agonists
Psychotropic drug metabolism may be impacted by factors such as: -
CORRECT-ANSWERS-age
-smoking
-caffeine intake
-other medications