Psychopharmacology Drugs the Brain And Behavior 4TH Edition meyer Nursing
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Test Bank
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,Psychopharmacology Drugs the Brain And Behavior 4TH Edition meyer Nursing u u u u u u u wu u u
Test Bank
wu u
Test Bank w
to accompany
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Psychopharmacology, 4th Edition w w
Meyer w• wQuenzer
Chapter 1: Principles of Pharmacology w w w w
Multiple Choice w
1. w refer(s) to specific molecular changes that occur when a drug binds to a
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wparticular target site or receptor, while w are the resulting widespread
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walterationsin function. w w
a. Drug action; therapeutic effects
w w w
b. Side effects; drug effects
w w w
c. Therapeutic effects; side effects w w w
d. Drug action; drug effects w w w
Answer: d w
Textbook Reference: Pharmacology: The Science of Drug Action
w w w w w w w
2. After drug administration has occurred, the amount of drug in the blood that is free
w w w w w w w w w w w w w w
tobind at specific target sites is referred to as
w w w w w w w w w w
a. the therapeutic dose.
w w
b. first-pass effects. w
c. bioavailability.
d. ED50.
Answer: c w
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
w w w w w w
3. The specific molecular changes that occur when a drug binds to a particular target
w w w w w w w w w w w w w
wsiteor receptor are referred to as
w w w w w w
a. drug effects. w
b. drug action. w
c. side effects. w
d. placebo effects. w
Answer: b w
Textbook Reference: Pharmacology: The Science of Drug Action
w w w w w w w
4. Which of the following is not a possible explanation for placebo effects?
w w w w w w w w w w w
a. Pavlovian conditioning w
b. Genetic variation w
c. Drug competition w
d. Expectation of outcome w w
Answer: c w
Textbook Reference: Pharmacology: The Science of Drug Action
w w w w w w w
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,Psychopharmacology Drugs the Brain And Behavior 4TH Edition meyer Nursing u u u u u u u wu u u
Test Bank
wu u
5. The administration of oxytocin has been proposed as a treatment for autism. w w w w w w w w w w
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: c w
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
w w w w w w
6. Which factor does not affect the pharmacokinetics of a drug?
w w w w w w w w w
a. Route of administration
w w
b. Lipid solubility
w
c. Depot binding w
d. Drug action w
Answer: d w
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
w w w w w w
7. First-pass metabolism occurs when drugs are taken
w w w w w w
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: a w
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
w w w w w w
8. The area postrema is one area in the brain where the
w w is not complete.
w w w w w w w w w w
a. cerebrospinal fluid w
b. blood–brain barrier w
c. choroid plexus w
d. phospholipid membrane w
Answer: b w
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
w w w w w w
9. First-pass metabolism occurs with orally administered drugs because
w w w w w w w
a. their absorption is slowed by food.
w w w w w
b. drugs absorbed into the bloodstream from the stomach go to the liver on the way
w w w w w w w w w w w w w w
togeneral circulation.
w w w
c. drugs must first survive the acidic environment of the stomach.
w w w w w w w w w
d. salivary enzymes in the mouth begin the process of metabolism.
w w w w w w w w w
Answer: b w
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
w w w w w w
10. Toxic substances in the blood trigger a vomiting response by activating the
w w w w w w w w w w w
a. blood–brain barrier. w
b. choroid plexus. w
c. area postrema.
w
d. median eminence. w
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, Psychopharmacology Drugs the Brain And Behavior 4TH Edition meyer Nursingu u u u u u u wu u u
Test Bank
wu u
Answer: c w
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
w w w w w w
11. Drugs administered _ w have the most rapid onset of action. w w w w w w w
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer: d w
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
w w w w w w
12. Ionization of a drug depends on the
w w of the solution and the
w w w w w w w w ofthe
drug.
w
a. pH; pKa
w
b. pKa; pH w
c. concentration; lipid solubility w w
d. pH; concentration
w
Answer: a w
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
w w w w w w
13. The absorption of a drug depends on all of the following except
w w w w w w w w w w w
a. lipid solubility.
w
b. ionization.
c. body temperature.
w
d. the concentration of the drug.
w w w w
Answer: c w
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
w w w w w w
14. Drugs that are wshould be avoided by women of childbearing age.
w w w w w w w w
a. teratogenic
b. able to cross the placental barrier
w w w w w
c. psychoactive
d. highly lipid-soluble
w
Answer: a w
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
w w w w w w
15. Agents that induce developmental abnormalities in a fetus are known as
w w w w w w w w w w
a. psychoactive drugs. w
b. illicit drugs.
w
c. teratogens.
d. placental drugs. w
Answer: c w
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
w w w w w w
16. Depot binding is said to occur when drugs
w w w w w w w
a. bind to their target sites.
w w w w
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