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CMB1004 Excitable Cells Exam Questions and Answers

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CMB1004 Excitable Cells Exam Questions and Answers What are the four regions of a neurone? - Answer-Dendrites Cell Body Axon Axon Terminal Define an excitable cell - Answer-Any cell capable of generating an action potential Describe how the resting potential is maintained - Answer-Cell conta...

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CMB1004 Excitable Cells Exam
Questions and Answers

What are the four regions of a neurone? - Answer✔✔-Dendrites


Cell Body


Axon


Axon Terminal


Define an excitable cell - Answer✔✔-Any cell capable of generating an action potential


Describe how the resting potential is maintained - Answer✔✔-Cell contains slight -ve charge (70mv)


Maintained via high permeability of membrane to K+ and active transport of Na+ across membrane


Define an action potential - Answer✔✔-A rapid change in membrane potential


What is the equilibrium potential? - Answer✔✔-The point at which the electrical gradient of the cell is

equal and opposite to the concentration gradient


What is the Nernst equation? - Answer✔✔-


What occurs at each stage of an action potentials generation? - Answer✔✔-Depolarisation: Membrane

potential increases from RMP


Repolarisation: Membrane potential decreases following depolarisation


Hyperpolarisation: Membrane potential falls below RMP

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FIRST PUBLISH SEPTEMBER 2024


Describe the activity of voltage gated ion channels during action potential generation - Answer✔✔-1)

Resting state, no gates open


2) Slow rising phase, some Na+ gates open, small amounts of Na+ enters cell


3) Rapid rising phase, all Na+ gates open, some K+ gates open


4) Early repolarisation, all K+ channels open, some Na+ closed


5) Hyperpolarisation, all Na+ closed, some K+ open


Define absolute refractory period - Answer✔✔-The period immediately following an action potential

generation during which no action potential can be generated regardless of stimulus size


Define relative refractory period - Answer✔✔-The period during hyperpolarisation where an abnormally

large stimulus can generate an action potential


How is the velocity of an action potential increased - Answer✔✔-Increase the diameter of the axon


Increase the membrane resistance by insulating with myelin sheath


Define myelination - Answer✔✔-The process by which axons are insulated with schwann cell

membranes to prevent loss of charge down the axon body


What is saltatory conduction? - Answer✔✔-Action potentials "jump" between areas of unmyelinated

axons called nodes of Ranvier, increasing transmission of the action potential


What is an endplate potential? - Answer✔✔-Depolarisation of the postsynaptic cell to a level halfway

between the equilibrium potential of the two ions (Na+ and K+ typically) involved




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