HTHSCI 3I03 – Immunology
Question bank with complete
History of Immunology.
answers |+650 Q & A
1. History of Immunology
2. Innate Immunity I
3. Innate Immunity II
4. Innate Immunity III
5. Innate Immunity IV
6. Adaptive Immunity I
7. Adaptive Immunity II
8. Generation of Diversity
9. Development of T cells
10. Activation of Naive T cell and Killer CD8
11. CD4+ T cells
12. T cell Regulation and Memory
13. B Cell Development
14. T-cell Dependent Antibody Production
15. Antibody Effector Functions
16. Memory
17. Mucosal Immunity
18. Intrinsic Immunity
19. Adaptive Immunity
20. Vaccines and Vaccine immunology
, 1-14 of 14
1. Humoral immunity: Soluble products in body fluids were responsible for immune
protection (anti-serum)
2. Cellular immunity: Specialized cells had the capacity to neutralize and engulf
infectious agents
, Two philosophies of immunology
Illness can be transmitted by microorganisms
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Germ theory of disease
- Regarded as the father of vaccination (though he was not the first to inoculate
cowpox as smallpox prevention)
- Noted that milkmaids rarely developed smallpox
- Rationalized that exposure to cowpox could prevent smallpox
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Edward Anthony Jenner
Proposed the idea that cells which ate bacterium (phagocytes) were responsible for
immune protection
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Elie Metchnikoff
, - Discovered that microorganisms caused fermentation and developed the technique
of pasteurization
- Discovered that microorganisms cannot produce illness if they are dead
- Observed that animals exposed to dead microorganisms could not be infected
upon subsequent exposure to live microorganisms
- Invented novel method for immunization based on inoculation with dead
microorganisms
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Louis Pasteur
- Smallpox survivor
- Observed inoculation technique while living in Turkey
- Brought the technique to Britain and met significant resistance but eventually
acceptance
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Lady Mary Wortley Montagu
Defined criteria to link a microorganism to a disease: Koch's postulates
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Robert Koch
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