1. Humoral: antibodies
2. Cell-mediated: helper and effector T cells
Two arms of adaptive immunity
, Organized lymphoid tissue below the skin, comprised of lymphocytes and
Langerhans cells (antigen presenting dendritic cells of the epidermis).
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Cutaneous immune system
Sample and deliver antigens to underlying lymphoid tissue (including viral antigens)
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M cells
• Produce cytokines
• Replicate and divide (expand)
• Kill cells displaying the peptide (T lymphocytes)
• Produce antibodies (B lymphocytes)
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Following binding of epitopes or peptides, B lymphocytes and T
lymphocytes:...
Sample antigens and migrate to regional lymph nodes to present information to T
lymphocytes and to directly activate B lymphocytes.
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